Insulin signaling to the glomerular podocyte is critical for normal kidney function. - Wikidata - awgldk - TriplyDB

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

http://www.wikidata.org/entity/Q42110064

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Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy Selective Insulin Resistance in the Kidney Podocytes Toll-like receptor activation: from renal inflammation to fibrosis Roles of renal proximal tubule transport in acid/base balance and blood pressure regulation New experimental models of diabetic nephropathy in mice models of type 2 diabetes: efforts to replicate human nephropathy Free Fatty acids and their metabolism affect function and survival of podocytes Molecular mechanisms of diabetic kidney disease Pericytes, an overlooked player in vascular pathobiology Proteomics and systems biology for understanding diabetic nephropathy Dysregulated nephrin in diabetic nephropathy of type 2 diabetes: a cross sectional study 2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.Dedifferentiation of immortalized human podocytes in response to transforming growth factor-β: a model for diabetic podocytopathy.Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice Hydrogen sulfide alleviates cardiac contractile dysfunction in an Akt2-knockout murine model of insulin resistance: role of mitochondrial injury and apoptosis.Representing kidney development using the gene ontology.Podocytes, signaling pathways, and vascular factors in diabetic kidney disease Normoglycemic diabetic nephropathy: the role of insulin resistance.Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of Alport syndrome The incidence of albuminuria after bariatric surgery and usual care in Swedish Obese Subjects (SOS): a prospective controlled intervention trial.GIV/girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin.Urinary miR-29 correlates with albuminuria and carotid intima-media thickness in type 2 diabetes patients.Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.Podocyte biology for the bedside Insulin signaling: implications for podocyte biology in diabetic kidney disease.TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression.Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy Nutrient sensing, autophagy, and diabetic nephropathy.WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization.Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes The Envy of Scholars: Applying the Lessons of the Framingham Heart Study to the Prevention of Chronic Kidney Disease Diet-Induced Podocyte Dysfunction in Drosophila and Mammals.Podocyte-specific loss of Cdc42 leads to congenital nephropathy High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach Treatment strategy for type 2 diabetes from the perspective of systemic vascular protection and insulin resistance.Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model.Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.

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P2860

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

http://www.wikidata.org/entity/Q42110064

description

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name

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

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Insulin signaling to the glomerular podocyte is critical for normal kidney function.

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type

label

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

@en

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

@nl

prefLabel

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

@en

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

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J.CMET.2010.08.015

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Cell Metabolism

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Insulin signaling to the glomerular podocyte is critical for normal kidney function.

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Andrew M Herzenberg

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Christopher J Caunt

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Deborah A Pons

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Gavin I Welsh

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Hermann Pavenstädt

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Jeremy M Tavaré

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Lorna J Hale

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Marie Jeansson

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Mervyn J Miles

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Moin A Saleem

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P2860

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Global and societal implications of the diabetes epidemic

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision

Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.

High-Q dynamic force microscopy in liquid and its application to living cells.

Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells.

The relationship between proteinuria and coronary risk: a systematic review and meta-analysis

Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus.

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329-340

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10.1016/J.CMET.2010.08.015

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4

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12

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Peter Mathieson

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2010-10-01T00:00:00Z

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47299667

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