Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening. - Wikidata - awgldk - TriplyDB

Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.

Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.

http://www.wikidata.org/entity/Q42112205

about

Next-generation antimicrobials: from chemical biology to first-in-class drugs In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered Growth A genomic and evolutionary approach reveals non-genetic drug resistance in malaria UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters Application of multi-target phytotherapeutic concept in malaria drug discovery: a systems biology approach in biomarker identification Effects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamine P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action A novel flow cytometric hemozoin detection assay for real-time sensitivity testing of Plasmodium falciparum Optimization of a Fluorescence-Based Assay for Large-Scale Drug Screening against Babesia and Theileria Parasites Targeting Lysine Deacetylases (KDACs) in Parasites Inhibition of an Erythrocyte Tyrosine Kinase with Imatinib Prevents Plasmodium falciparum Egress and Terminates Parasitemia Hemozoin and antimalarial drug discovery Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity.In vitro activity of pyrvinium pamoate against Entamoeba histolytica and Giardia intestinalis using radiolabelled thymidine incorporation and an SYBR Green I-based fluorescence assay.Hybrid median filter background estimator for correcting distortions in microtiter plate data.Analysis of ex vivo drug response data of Plasmodium clinical isolates: the pros and cons of different computer programs and online platforms.High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.Plasmodium falciparum: development of a transgenic line for screening antimalarials using firefly luciferase as the reporter.Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia.Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads.Polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 genes are associated with reduced in vitro activities of quinine in Plasmodium falciparum isolates from western Kenya Evaluation of a fluorescence-based method for antibabesial drug screening Transplacentally transferred functional antibodies against Plasmodium falciparum decrease with age.Validating a firefly luciferase-based high-throughput screening assay for antimalarial drug discovery.High content live cell imaging for the discovery of new antimalarial marine natural products Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screening Whole-cell in vitro screening for gametocytocidal compounds.The bis(indolyl)imidazole alkaloid nortopsentin a exhibits antiplasmodial activity.Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication Antimalarial action of artesunate involves DNA damage mediated by reactive oxygen species Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials.

P2860

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P2860

Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.

http://www.wikidata.org/entity/Q42112205

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Assessment and continued valid ...... use in malaria drug screening.

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Assessment and continued valid ...... use in malaria drug screening.

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type

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Assessment and continued valid ...... use in malaria drug screening.

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Assessment and continued valid ...... use in malaria drug screening.

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prefLabel

Assessment and continued valid ...... use in malaria drug screening.

@en

Assessment and continued valid ...... use in malaria drug screening.

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Antimicrobial Agents and Chemotherapy

P1476

Assessment and continued valid ...... use in malaria drug screening.

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Jacob D Johnson

http://www.w3.org/2001/XMLSchema#string

Lucia Gerena

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Miriam Lopez-Sanchez

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Norma E Roncal

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Norman C Waters

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Richard A Dennull

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P2860

Human malaria parasites in continuous culture

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Studies of the disposition and metabolism of mefloquine HCl (WR 142,490), a quinolinemethanol antimalarial, in the rat. Limited studies with an analog, WR 30,090

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

Drug resistant falciparum malaria: clinical consequences and strategies for prevention.

A database of antimalarial drug resistance.

Combination of drug level measurement and parasite genotyping data for improved assessment of amodiaquine and sulfadoxine-pyrimethamine efficacies in treating Plasmodium falciparum malaria in Gabonese children.

Epidemiology of drug-resistant malaria.

Searching for new antimalarial therapeutics amongst known drugs.

High-throughput Plasmodium falciparum growth assay for malaria drug discovery.

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1926-1933

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10.1128/AAC.01607-06

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6

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51

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6435190

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17371812

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1891422

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