The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease.
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Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysisUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationThe role of the ubiquitin-proteasome system in Agrobacterium tumefaciens-mediated genetic transformation of plantsProteasome subunit Rpn13 is a novel ubiquitin receptorSolution structure of the E3 ligase HOIL-1 Ubl domainThe retroviral proteinase active site and the N-terminus of Ddi1 are required for repression of protein secretion.Targeting proteins for degradationRecognition and processing of ubiquitin-protein conjugates by the proteasomeHuman DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.ATM-mediated transcriptional and developmental responses to gamma-rays in ArabidopsisComponents of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins.Rad23 escapes degradation because it lacks a proteasome initiation regionDelivery of ubiquitinated substrates to protein-unfolding machines.Sequestration of highly expressed mRNAs in cytoplasmic granules, P-bodies, and stress granules enhances cell viability.Transfer of Ho endonuclease and Ufo1 to the proteasome by the UbL-UbA shuttle protein, Ddi1, analysed by complex formation in vitro.Loss of the extraproteasomal ubiquitin receptor Rings lost impairs ring canal growth in Drosophila oogenesis.Regulated protein turnover: snapshots of the proteasome in action.A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cellsRpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasomeRecognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome systemMechanisms for countering oxidative stress and damage in retinal pigment epithelium.Ubiquitin-like domains can target to the proteasome but proteolysis requires a disordered region.Affinity purification strategy to capture human endogenous proteasome complexes diversity and to identify proteasome-interacting proteins.Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.Defining how ubiquitin receptors hHR23a and S5a bind polyubiquitin.Catalytically Active Proteasomes Function Predominantly in the Cytosol.Yeast UBL-UBA proteins have partially redundant functions in cell cycle control.DNA-damage-inducible 1 protein (Ddi1) contains an uncharacteristic ubiquitin-like domain that binds ubiquitin.Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.HIV proteinase inhibitors target the Ddi1-like protein of Leishmania parasites.Different domains of the UBL-UBA ubiquitin receptor, Ddi1/Vsm1, are involved in its multiple cellular roles.Unique role for the UbL-UbA protein Ddi1 in turnover of SCFUfo1 complexes.Comprehensive profiling of lysine ubiquitome reveals diverse functions of lysine ubiquitination in common wheatUV and arsenate toxicity: a specific and sensitive yeast bioluminescence assay.Nuclear import of ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system.Inhibition of calpain-1 stabilizes TCF11/Nrf1 but does not affect its activation in response to proteasome inhibitionThe defective proteasome but not substrate recognition function is responsible for the null phenotypes of the Arabidopsis proteasome subunit RPN10
P2860
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P2860
The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@en
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@nl
type
label
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@en
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@nl
prefLabel
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@en
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@nl
P2093
P2860
P1476
The DNA damage-inducible UbL-U ...... egradation of Ho endonuclease.
@en
P2093
Anya Bakhrat
Dina Raveh
Ludmila Kaplun
Nitzan Shabek
Regina Tzirkin
P2860
P304
P356
10.1128/MCB.25.13.5355-5362.2005
P407
P577
2005-07-01T00:00:00Z