about
DNA damage response-mediated degradation of Ho endonuclease via the ubiquitin system involves its nuclear export.Generation of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5.New interacting partners of the F-box protein Ufo1 of yeast.Multiple sclerosis autoantigen myelin basic protein escapes control by ubiquitination during proteasomal degradationThe N-terminal domain of MyoD is necessary and sufficient for its nuclear localization-dependent degradation by the ubiquitin systemThe ubiquitin-proteasome system and activation of NF-κB: involvement of the ubiquitin ligase KPC1 in p105 processing and tumor suppressionThe lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore.The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal.ABIN-1 negatively regulates NF-kappaB by inhibiting processing of the p105 precursor.The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease.Unique role for the UbL-UbA protein Ddi1 in turnover of SCFUfo1 complexes.KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor.The F-box protein, Ufo1, maintains genome stability by recruiting the yeast mating switch endonuclease, Ho, for rapid proteasome degradation.Role of the ubiquitin ligase KPC1 in NF-κB activation and tumor suppression
P50
Q27930230-C221FC32-1183-4814-91FC-2FE2E419FF30Q27935636-663E0EA8-A55E-4790-88BB-D987E169A42BQ33379170-FE3783F2-AA9E-43FB-9218-B1CD2DD5F47CQ33793002-4F674842-BC35-46BE-8A68-A40DBB79F311Q34845706-35EBC62B-9A63-4F40-80E8-EFF760BB13EAQ36998038-B2CD0E24-D050-48F7-A84D-0C531C42E459Q38057666-2FDA0CCE-105F-434C-86B3-67B58119A752Q38799026-48D03A7D-C053-43CB-A308-4FFE99086712Q39298346-10156BEA-8626-45B5-AEC3-8C8E2E5F6F66Q39810390-DF77C81F-00A8-40A7-B48D-D639441FA7FEQ42115583-CED522BB-457B-4D53-8C80-12CD8ECFA620Q42196272-E68B91E1-B818-434C-8770-4F95882DD0CEQ42475469-DBDA87FF-4693-46C1-B7C5-1174D25B7619Q51793392-4B70E662-022D-4FA1-BC3B-BD6D5544C8E5Q53624713-57D889A6-CB15-4700-AB55-FAA9CD54E967Q59479950-4B6BB4CE-2117-4D08-A145-AE73984858B4
P50
name
Yelena Kravtsova-Ivantsiv
@en
Yelena Kravtsova-Ivantsiv
@nl
type
label
Yelena Kravtsova-Ivantsiv
@en
Yelena Kravtsova-Ivantsiv
@nl
prefLabel
Yelena Kravtsova-Ivantsiv
@en
Yelena Kravtsova-Ivantsiv
@nl