The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.
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Initiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodelingThe cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elementsRole for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm.Cohesin complexes with a potential to link mammalian meiosis to cancerExpression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway.A Common Polymorphism within the IGF2 Imprinting Control Region Is Associated with Parent of Origin Specific Effects in Infantile HemangiomasComparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions.SOHLH1 and SOHLH2 directly down-regulate STIMULATED BY RETINOIC ACID 8 (STRA8) expression.CTCF contributes in a critical way to spermatogenesis and male fertility.Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.Expression analysis of BORIS during pluripotent, differentiated, cancerous, and non-cancerous cell states.Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.Nuclease Footprints in Sperm Project Past and Future Chromatin Regulatory Events.CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin.Expression of the cancer-testis antigen BORIS correlates with prostate cancer.Induced DNA demethylation can reshape chromatin topology at the IGF2-H19 locus.The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.Transcriptional programs that control expression of the autoimmune regulator gene Aire.Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations.The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes.Common and low-frequency variants associated with genome-wide recombination rate.Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect.A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis.DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism.Discovering a binary CTCF code with a little help from BORIS.The Diverging Routes of BORIS and CTCF: An Interactomic and Phylogenomic Analysis.BORIS: a key regulator of cancer stemnessHistone Methyltransferase mRNA Levels Increase in Response to Curative Hormone Treatment for Cryptorchidism-Dependent Male Infertility
P2860
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P2860
The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
The male germ cell gene regula ...... composition-dependent manner.
@en
The male germ cell gene regula ...... composition-dependent manner.
@nl
type
label
The male germ cell gene regula ...... composition-dependent manner.
@en
The male germ cell gene regula ...... composition-dependent manner.
@nl
prefLabel
The male germ cell gene regula ...... composition-dependent manner.
@en
The male germ cell gene regula ...... composition-dependent manner.
@nl
P2093
P2860
P50
P356
P1476
The male germ cell gene regula ...... composition-dependent manner.
@en
P2093
Frank Grosveld
Frank Sleutels
Helen Heath
J Anton Grootegoed
Jan Christian Bryne
Lisa Caesar
M Dolores Delgado
Marek Bartkuhn
Michael van der Reijden
Niels Galjart
P2860
P2888
P356
10.1186/1756-8935-5-8
P577
2012-06-18T00:00:00Z
P5875
P6179
1030344317