Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast.
about
Comparative genomics and molecular dynamics of DNA repeats in eukaryotesMcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.Replication stress in Mammalian cells and its consequences for mitosisReplication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.Checkpoint independence of most DNA replication origins in fission yeastNovel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation.Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae.Regulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea.Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complexSystematic identification of fragile sites via genome-wide location analysis of gamma-H2AX.Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells.Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formationCleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpointNovel checkpoint pathway organization promotes genome stability in stationary-phase yeast cells.Identification of early replicating fragile sites that contribute to genome instabilityFeatures of trinucleotide repeat instability in vivo.RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cellsCheckpoint responses to unusual structures formed by DNA repeats.Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae.Regulation of DNA replication by the S-phase DNA damage checkpoint.The S-phase checkpoint: targeting the replication fork.Surviving chromosome replication: the many roles of the S-phase checkpoint pathway.Enigmatic roles of Mcm10 in DNA replicationThe DNA damage checkpoint response to replication stress: A Game of Forks.MCM10: one tool for all-Integrity, maintenance and damage control.Homologous recombination as a replication fork escort: fork-protection and recovery.Replication initiation and genome instability: a crossroads for DNA and RNA synthesis.Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex.An intrinsic checkpoint model for regulation of replication origins.Environmental change drives accelerated adaptation through stimulated copy number variation.Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae.Fbh1 limits Rad51-dependent recombination at blocked replication forks.Role of PCNA and RFC in promoting Mus81-complex activity.Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells.Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair.Genome rearrangements caused by depletion of essential DNA replication proteins in Saccharomyces cerevisiae.Absence of Non-histone Protein Complexes at Natural Chromosomal Pause Sites Results in Reduced Replication Pausing in Aging Yeast Cells.Four pillars of the S-phase checkpoint.
P2860
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P2860
Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Genome-wide replication profil ...... reveal fragile sites in yeast.
@en
Genome-wide replication profil ...... reveal fragile sites in yeast.
@nl
type
label
Genome-wide replication profil ...... reveal fragile sites in yeast.
@en
Genome-wide replication profil ...... reveal fragile sites in yeast.
@nl
prefLabel
Genome-wide replication profil ...... reveal fragile sites in yeast.
@en
Genome-wide replication profil ...... reveal fragile sites in yeast.
@nl
P2093
P2860
P356
P1433
P1476
Genome-wide replication profil ...... reveal fragile sites in yeast.
@en
P2093
Anja-Katrin Bielinsky
Duncan J Clarke
Justin Haworth
Miruthubashini Raveendranathan
Sharbani Chattopadhyay
Yung-Tsi Bolon
P2860
P304
P356
10.1038/SJ.EMBOJ.7601251
P407
P577
2006-08-03T00:00:00Z