Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
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Platelets in Pulmonary Immune Responses and Inflammatory Lung DiseasesPlatelets and their role in cancer evolution and immune systemPlatelets in inflammation: regulation of leukocyte activities and vascular repairPlatelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.Platelets: No longer bystanders in liver diseasePodoplanin: emerging functions in development, the immune system, and cancerSyk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.Platelet ITAM signaling is critical for vascular integrity in inflammation.Mutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity.CLEC-2 expression is maintained on activated platelets and on platelet microparticles.Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomasGeneration of pure lymphatic endothelial cells from human pluripotent stem cells and their therapeutic effects on wound repair.Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formationPlatelet immunoreceptor tyrosine-based activation motif (ITAM) signaling and vascular integrity.The impact of Aggrus/podoplanin on platelet aggregation and tumour metastasis.Lymphatic vessels: new targets for the treatment of inflammatory diseases.Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?Platelets and Their Interactions with Other Immune CellsPlatelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.A Case of Abnormal Lymphatic-Like Differentiation and Endothelial Progenitor Cell Activation in Neovascularization Associated with Hemi-Retinal Vein Occlusion.The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
P2860
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P2860
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@en
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@nl
type
label
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@en
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@nl
prefLabel
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@en
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
@nl
P2093
P2860
P50
P1476
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2
@en
P2093
P2860
P304
P356
10.1111/J.1538-7836.2011.04614.X
P577
2012-03-01T00:00:00Z