PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility.
about
Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexinIQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Wiskott-Aldrich syndrome protein (WASp) and N-WASp are involved in the regulation of NK-cell migration upon NKG2D activationPhosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell ActivationHIV-1 matrix dependent membrane targeting is regulated by Gag mRNA traffickingStructural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3APIP kinases define PI4,5P₂signaling specificity by association with effectorsCa2+-activated IK1 channels associate with lipid rafts upon cell swelling and mediate volume recoveryArf6 and microtubules in adhesion-dependent trafficking of lipid rafts.Spatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activationActivated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42Protein kinase A regulates 3-phosphatidylinositide dynamics during platelet-derived growth factor-induced membrane ruffling and chemotaxisCholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane.Tip growth: signaling in the apical dome.Coordination between extrinsic extracellular matrix cues and intrinsic responses to orient the centrosome in polarizing cerebellar granule neuronsAxon guidance: asymmetric signaling orients polarized outgrowth.Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.Cholesterol sulfate alters substrate preference of matrix metalloproteinase-7 and promotes degradations of pericellular laminin-332 and fibronectinSpecific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domainPhosphatidylinositol 4,5-bisphosphate: targeted production and signalingDynamics of membranes driven by actin polymerization.Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2.IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway.IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton.Phosphatidylinositol-4,5-bisphosphate is enriched in granulovacuolar degeneration bodies and neurofibrillary tanglesStructural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles.Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly.Coincidence detection in phosphoinositide signaling.Plasma membrane phosphoinositide organization by protein electrostatics.PIP2 signaling, an integrator of cell polarity and vesicle trafficking in directionally migrating cells.Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides.Lipid rafts in lymphocyte activation and migration.The region-specific activities of lipid rafts during axon growth and guidance.Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signallingStructural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein.Invasive cells in animals and plants: searching for LECA machineries in later eukaryotic lifeLipids and lipid modifications in the regulation of membrane traffic.
P2860
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P2860
PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@en
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@nl
type
label
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@en
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@nl
prefLabel
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@en
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@nl
P2860
P356
P1476
PI(4,5)P2-dependent microdomai ...... control leading edge motility.
@en
P2093
Pico Caroni
Tamara Golub
P2860
P304
P356
10.1083/JCB.200407058
P407
P577
2005-04-04T00:00:00Z