Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
about
Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activityComprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein networkBinding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cellsErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.CLIPs and CLASPs and cellular dynamicsOncogenic function of DACT1 in colon cancer through the regulation of β-cateninIdentification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEFAsef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migrationRegulation of IRSp53-dependent filopodial dynamics by antagonism between 14-3-3 binding and SH3-mediated localization.The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migrationGSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosomeAsef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation elementThe nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytesARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motilitySir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signalingAPC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment.Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapseProtein kinase C iota: human oncogene, prognostic marker and therapeutic targetThe Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-SrcKLHL1/MRP2 mediates neurite outgrowth in a glycogen synthase kinase 3beta-dependent mannerThe integrin-actin connection, an eternal love affairSpatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cellsInhibition of medulloblastoma cell invasion by SlitGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsExamination of actin and microtubule dependent APC localisations in living mammalian cells.Cell polarity signaling in the plasticity of cancer cell invasivenessRho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamicsRho GTPases in collective cell migrationMammalian diaphanous-related formin 1 regulates GSK3β-dependent microtubule dynamics required for T cell migratory polarizationKif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway.Apc mutation enhances PyMT-induced mammary tumorigenesisWho needs microtubules? Myogenic reorganization of MTOC, Golgi complex and ER exit sites persists despite lack of normal microtubule tracksErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.DAAM1 is a formin required for centrosome re-orientation during cell migrationAn aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activationLung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrityDirect binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cellsThe APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesisThe tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edgeThe focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
P2860
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P2860
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2003
@ast
scientific journal article
@en
vedecký článok (publikovaný 2003/02/13)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/13)
@nl
наукова стаття, опублікована в лютому 2003
@uk
مقالة علمية (نشرت في 13-2-2003)
@ar
name
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@ast
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@en
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@nl
type
label
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@ast
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@en
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@nl
prefLabel
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@ast
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@en
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@nl
P3181
P356
P1433
P1476
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
@en
P2093
Sandrine Etienne-Manneville
P2888
P304
P3181
P356
10.1038/NATURE01423
P407
P577
2003-02-13T00:00:00Z
P6179
1022051159