Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
about
Role of ROS and RNS Sources in Physiological and Pathological ConditionsSphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking.SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.Regulated Entry of Hepatitis C Virus into Hepatocytes.Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagyLevetiracetam mitigates doxorubicin-induced DNA and synaptic damage in neuronsA current pharmacologic agent versus the promise of next generation therapeutics to ameliorate protein misfolding and/or aggregation diseases.TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin.SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells.Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease.MAMs are attractive targets for bacterial repurposing of the host cell: MAM-functions might be key for undermining an infected cell.Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain.The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons.Fingolimod suppresses neuronal autophagy through the mTOR/p70S6K pathway and alleviates ischemic brain damage in mice.TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition.Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes.Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative Disorders.
P2860
Q26740342-614872FC-3B45-493C-A8EB-90EA72BF4512Q30275525-9D7A18E0-1C34-4373-8C11-9EE8E56F3B77Q30853652-E481E048-FE4F-47F7-85F8-2A7539A8FA07Q33753913-57E89E44-4989-4ECC-8CCF-E81DB16EDDD0Q33902931-1141DB13-A254-4E33-B780-7577C4A39392Q36607525-6B7E23C0-833D-4CB6-B7BA-9720274C457FQ36890652-C145B064-C137-47E5-B2A1-B1E49DE3E507Q37004163-1AF802C0-C45E-4834-ADAB-5B518141E5A4Q37610214-B4763753-6AC6-47A5-B55B-8E15805E68AEQ38755161-A166414B-CC04-4DC3-91EF-0BF6977474CFQ38973133-8E8DFB71-F081-4FC6-BEA2-8A3944A8FB27Q40394343-6E4C0C3A-3B60-4138-923A-752589414BD0Q41335248-0CB53E9A-B8B5-4C8E-807D-37DDD56CE561Q42173513-476C7D94-FE45-40A8-9B20-98B875653783Q47144572-0001918E-A29F-446E-A757-70A8BF05AB42Q49714600-42FD3A93-87E5-4DAD-A1AB-05294303A386Q54111173-F75B770E-D146-4091-A78D-32082F1D21FCQ55122433-0DB79EC1-8301-44A7-B6C0-0DF31B19A4BE
P2860
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@en
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@nl
type
label
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@en
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@nl
prefLabel
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@en
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy.
@nl
P2093
P2860
P50
P356
P1433
P1476
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy
@en
P2093
Andrey S Tsvetkov
Erin E Furr-Stimming
Steven Finkbeiner
P2860
P2888
P356
10.1038/SREP15213
P407
P577
2015-10-19T00:00:00Z