Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.
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Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric IntermediateThe in vitro characterization of polyene glycosyltransferases AmphDI and NysDIVariations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilyPost-PKS tailoring steps of a disaccharide-containing polyene NPP in Pseudonocardia autotrophicaSelvamicin, an atypical antifungal polyene from two alternative genomic contextsIdentification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015.The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism.Biosynthesis and pathway engineering of antifungal polyene macrolides in actinomycetes.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation.New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei.Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies.Target-specific identification and characterization of the putative gene cluster for brasilinolide biosynthesis revealing the mechanistic insights and combinatorial synthetic utility of 2-deoxy-l-fucose biosynthetic enzymes.Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment.Versatility of enzymes catalyzing late steps in polyene 67-121C biosynthesis.Improved recovery and biological activities of an engineered polyene NPP analogue in Pseudonocardia autotrophica.Biosynthesis of new lipopentapeptides by an engineered strain of Streptomyces sp.Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica.
P2860
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P2860
Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
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2006年學術文章
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name
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@en
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@nl
type
label
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@en
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@nl
prefLabel
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@en
Characterization of the P450 m ...... tatin in Streptomyces noursei.
@nl
P2093
P2860
P1476
Characterization of the P450 m ...... statin in Streptomyces noursei
@en
P2093
Håvard Sletta
Olga Volokhan
Trond E Ellingsen
P2860
P304
P356
10.1128/AEM.72.4.2514-2519.2006
P407
P577
2006-04-01T00:00:00Z