Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
about
ATR suppresses endogenous DNA damage and allows completion of homologous recombination repairDNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repairFunctions of PARylation in DNA Damage Repair PathwaysRoles of RNA-Binding Proteins in DNA Damage ResponseReaders of poly(ADP-ribose): designed to be fit for purposeNon-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage SignalingInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapySam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ationProteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cellsLiquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).A genomic copy number variant analysis implicates the MBD5 and HNRNPU genes in Chinese children with infantile spasms and expands the clinical spectrum of 2q23.1 deletionDNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.Differential contribution of HP1 proteins to DNA end resection and homology-directed repair.Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.The role of hnRPUL1 involved in DNA damage response is related to PARP1.Inhibition of DNA damage repair by artificial activation of PARP with siDNA.The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damagePARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage.TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription FactorsARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP InhibitorsBiochemical mechanism of DSB end resection and its regulation.EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.Proteomic Analysis Implicates Dominant Alterations of RNA Metabolism and the Proteasome Pathway in the Cellular Response to Carbon-Ion IrradiationThe spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing.A BRCA1-interacting lncRNA regulates homologous recombination.Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction.TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.DNA damage, chromatin, and transcription: the trinity of aging.Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis.Non-coding RNAs in DNA damage and repair.Sharpening the ends for repair: mechanisms and regulation of DNA resection.Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombinationGenomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemiaCharity begins at home: non-coding RNA functions in DNA repairA flow cytometry-based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells.Cip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts.
P2860
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P2860
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Regulation of DNA-end resectio ...... and break signaling and repair
@en
Regulation of DNA-end resectio ...... and break signaling and repair
@nl
type
label
Regulation of DNA-end resectio ...... and break signaling and repair
@en
Regulation of DNA-end resectio ...... and break signaling and repair
@nl
prefLabel
Regulation of DNA-end resectio ...... and break signaling and repair
@en
Regulation of DNA-end resectio ...... and break signaling and repair
@nl
P2093
P2860
P50
P1433
P1476
Regulation of DNA-end resectio ...... and break signaling and repair
@en
P2093
A Malcolm R Taylor
Andre Rusch
Andrew N Blackford
Andrew S Turnell
Anoushka Thomas
J Ross Chapman
Julia Kzhyshkowska
Linda Baskcomb
Philippa Smith
Rachel Blundred
P2860
P304
P356
10.1016/J.MOLCEL.2011.12.035
P577
2012-02-01T00:00:00Z