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In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols.Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetateChloride and other anions inhibit dichloroacetate-induced inactivation of human liver GSTZ1 in a haplotype-dependent manner.Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass (Micropterus salmoides).Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate.Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1.Chloride concentrations in human hepatic cytosol and mitochondria are a function of age.Celecoxib influences steroid sulfonation catalyzed by human recombinant sulfotransferase 2A1.Sulfonation of 17beta-estradiol and inhibition of sulfotransferase activity by polychlorobiphenylols and celecoxib in channel catfish, Ictalurus punctatusInhibition of sulfotransferases by xenobiotics.Glucuronidation and sulfonation, in vitro, of the major endocrine-active metabolites of methoxychlor in the channel catfish, Ictalurus punctatus, and induction following treatment with 3-methylcholanthreneStimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells.Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta.cDNA and protein sequence of a major form of P450, CYP2L, in the hepatopancreas of the spiny lobster, Panulirus argus.Seasonal influences on PCB retention and biotransformation in fishAge-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity.Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus)The state of in vitro science for use in bioaccumulation assessments for fish.Steroid catabolism in marine and freshwater fish.Interactions of cytosolic sulfotransferases with xenobiotics.GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate.The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression.Preliminary X-ray crystallographic analysis of glutathione transferase zeta 1 (GSTZ1a-1a).Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate.Effects of Food Natural Products on the Biotransformation of PCBs.Intestinal and hepatic microsomal metabolism of testosterone and progesterone by a 3 alpha-hydroxysteroid dehydrogenase to the 3 alpha-hydroxy derivatives in the channel catfish, Ictalurus punctatus.Binding of 3-hydroxybenzo[a]pyrene to bovine hemoglobin and albumin.Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents.Increased toxicity of benzo(a)pyrene-7,8-dihydrodiol in the presence of polychlorobiphenylols.Unified gas chromatographic-mass spectrometric method for quantitating tyrosine metabolites in urine and plasma.Triclosan as a substrate and inhibitor of 3'-phosphoadenosine 5'-phosphosulfate-sulfotransferase and UDP-glucuronosyl transferase in human liver fractions.Liquid chromatography-tandem mass spectrometry method for the simultaneous determination of delta-ALA, tyrosine and creatinine in biological fluids.A multi-year study of hepatic biomarkers in coastal fishes from the Gulf of Mexico after the Deepwater Horizon Oil Spill.Biological effects of Byrsocarpus coccineus in vitro.Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine.Intestinal bioavailability and biotransformation of 3,3',4,4'-tetrachlorobiphenyl (CB 77) in in situ preparations of channel catfish following dietary induction of CYP1A.Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes.Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.Pharmacokinetics of Oral Dichloroacetate in Dogs
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Margaret O. James
@ast
Margaret O. James
@en
Margaret O. James
@es
Margaret O. James
@nl
Margaret O. James
@sl
type
label
Margaret O. James
@ast
Margaret O. James
@en
Margaret O. James
@es
Margaret O. James
@nl
Margaret O. James
@sl
prefLabel
Margaret O. James
@ast
Margaret O. James
@en
Margaret O. James
@es
Margaret O. James
@nl
Margaret O. James
@sl
P1053
A-8232-2011
P106
P1153
7402508193
P21
P31
P3829
P3835
margaret-james
P496
0000-0001-8778-9427