Biophysical studies of the c-MYC NHE III1 promoter: model quadruplex interactions with a cationic porphyrin.
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Molecules that target nucleophosmin for cancer treatment: an updateFinding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMRChemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-elementNucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA"One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1.Interactions of actinomycin D with human telomeric G-quadruplex DNA.Bcl-2 promoter sequence G-quadruplex interactions with three planar and non-planar cationic porphyrins: TMPyP4, TMPyP3, and TMPyP2.Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.Modeling complex equilibria in isothermal titration calorimetry experiments: thermodynamic parameters estimation for a three-binding-site modelMAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.Thermodynamics of nucleic acid "shape readout" by an aminosugarFirst International Meeting on Quadruplex DNA.Stability and kinetics of G-quadruplex structuresA hitchhiker's guide to G-quadruplex ligands.Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.Fluorescent probes for G-quadruplex structures.A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.In silico identification of novel ligands for G-quadruplex in the c-MYC promoter.A spectroscopic investigation of the interaction between c-MYC DNA and tetrapyridinoporphyrazinatozinc(II).Studies on the site and mode of TMPyP4 interactions with Bcl-2 promoter sequence G-Quadruplexes.Photosensitizers binding to nucleic acids as anticancer agents.Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation.Recognition and binding of human telomeric G-quadruplex DNA by unfolding protein 1.Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes.Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4Nucleophosmin C-terminal leukemia-associated domain interacts with G-rich quadruplex forming DNA.Biophysical characterization of an ensemble of intramolecular i-motifs formed by the human c-MYC NHE III1 P1 promoter mutant sequence.Elevated polyamines induce c-MYC overexpression by perturbing quadruplex-WC duplex equilibrium.Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes.DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes.Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes.Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models.Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase.Platinum(II) clovers targeting G-quadruplexes and their anticancer activities.Molecular Recognition of Parallel DNA Quadruplex d(TTAGGGT)4 by Mitoxantrone: Binding with 1:2 Stoichiometry Leading to Thermal Stabilization and Telomerase Inhibition.Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPEInteractions of Pt-ttpy with G-Quadruplexes Originating from Promoter Region of the c-myc Gene Deciphered by NMR and Gel Electrophoresis Analysis
P2860
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P2860
Biophysical studies of the c-MYC NHE III1 promoter: model quadruplex interactions with a cationic porphyrin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@en
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@nl
type
label
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@en
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@nl
prefLabel
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@en
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@nl
P2093
P2860
P1433
P1476
Biophysical studies of the c-M ...... ons with a cationic porphyrin.
@en
P2093
Derek Cashman
Edwin A Lewis
Kimberly Kaplan
Laurence H Hurley
Matthew W Freyer
Robert Buscaglia
P2860
P304
P356
10.1529/BIOPHYSJ.106.097246
P407
P577
2006-12-15T00:00:00Z