Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.
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Combining a Ru(II) "Building Block" and Rapid Screening Approach to Identify DNA Structure-Selective "Light Switch" Compounds.Strategies to Inhibit Myc and Their Clinical ApplicabilityNovel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA.Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Selective Targeting of G-Quadruplex Structures by a Benzothiazole-Based Binding Motif.Higher densities of Foxp3+ regulatory T cells are associated with better prognosis in triple-negative breast cancer.Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor.Preferential targeting of i-motifs and G-quadruplexes by small molecules.Resolving the Ligand-Binding Specificity in c-MYC G-Quadruplex DNA: Absolute Binding Free Energy Calculations and SPR Experiment.Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule.Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders.Chromatin dependencies in cancer and inflammation.Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins.Characterization of clinically used oral antiseptics as quadruplex-binding ligands.Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR.Benzothiazole hydrazones of furylbenzamides preferentially stabilize c-MYC and c-KIT1 promoter G-quadruplex DNAs.Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex
P2860
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P2860
Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@ast
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@en
type
label
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@ast
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@en
prefLabel
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@ast
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@en
P2093
P2860
P1433
P1476
Small Molecule Microarrays Ena ...... g Inhibitor of MYC Expression.
@en
P2093
Aleksandra Michalowski
Beverly A Mock
Elena Leon
John K Simmons
John S Schneekloth
Kenneth M Felsenstein
Lindsey B Saunders
Peter Gareiss
Shuling Zhang
P2860
P304
P356
10.1021/ACSCHEMBIO.5B00577
P577
2015-10-13T00:00:00Z