CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
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Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiriMutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri.Herpesvirus saimiri.Substitution of ras for the herpesvirus saimiri STP oncogene in lymphocyte transformationDownregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural hostAn animal model for Epstein-Barr virus (EBV)-associated lymphomagenesis in the human: malignant lymphoma induction of rabbits by EBV-related herpesvirus from cynomolgus.Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products.Development of herpesvirus-based episomally maintained gene delivery vectors.Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus SaimiriThe superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells.Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells.Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesvirusesRole of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP.Herpesvirus saimiri transforms human T-cell clones to stable growth without inducing resistance to apoptosis.A role for herpesvirus saimiri orf14 in transformation and persistent infection.The interleukin-17 gene of herpesvirus saimiri.STP and Tip are essential for herpesvirus saimiri oncogenicityAssociation of the viral oncoprotein STP-C488 with cellular ras.Higher proliferative capacity of T lymphocytes from patients with Crohn disease than from ulcerative colitis is disclosed by use of Herpesvirus saimiri-transformed T-cell lines.Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.The role of CD2 as a regulator of human T-cell cytokine production.The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells.Cytokine dependence of human to mouse graft-versus-host disease.Independence of herpesvirus-induced T cell lymphoma from viral cyclin D homologue.Rhadinovirus vector-derived human telomerase reverse transcriptase expression in primary T cells.Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation.Herpesvirus saimiri-based gene delivery vectors maintain heterologous expression throughout mouse embryonic stem cell differentiation in vitro.Membrane and transmembrane signaling in Herpesvirus saimiri-transformed human CD4(+) and CD8(+) T lymphocytes is ATM-independent.
P2860
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P2860
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@en
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@nl
type
label
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@en
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@nl
prefLabel
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@en
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@nl
P2093
P2860
P356
P1476
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes.
@en
P2093
Fleckenstein B
Fleischer B
Mittrücker HW
Müller-Fleckenstein I
P2860
P304
P356
10.1084/JEM.176.3.909
P407
P577
1992-09-01T00:00:00Z