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Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brainKynurenines in the mammalian brain: when physiology meets pathologyChanging the face of kynurenines and neurotoxicity: therapeutic considerationsFluctuations in endogenous kynurenic acid control hippocampal glutamate and memoryConcurrent quantification of tryptophan and its major metabolites.Fatigue in patients with lung cancer is related with accelerated tryptophan breakdown.Kynurenine pathway metabolites in humans: disease and healthy States.Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity.Plasticity of purine release during cerebral ischemia: clinical implications?Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient miceKynurenic Acid in the digestive system-new facts, new challenges.Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid.The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex.Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges.Preferential Disruption of Prefrontal GABAergic Function by Nanomolar Concentrations of the α7nACh Negative Modulator Kynurenic Acid.Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as "Glia Depressing Factor" (GDF).Kynurenic Acid Induces Impairment of Oligodendrocyte Viability: On the Role of Glutamatergic MechanismsThe kynurenine pathway and the brain: Challenges, controversies and promises.Kynurenines and Glutamate: Multiple Links and Therapeutic Implications.Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1.Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo.Enhanced sensitivity of medullary depressor neurons to N-methyl-D-aspartate-glycine site antagonists in the spontaneously hypertensive rat.Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat.Immunohistochemical studies of the kynurenine pathway in morpheaNovel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro.Presynaptic kynurenate-sensitive receptors inhibit glutamate release.Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid.Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures.Neuroactive metabolites of L-tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid. Effect of tryptophan loading.Micromolar brain levels of kynurenic acid are associated with a disruption of auditory sensory gating in the rat.Diclofenac increases the accumulation of kynurenate following tryptophan pretreatment in the rat: a possible factor contributing to its antihyperalgesic effect.Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats.Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia.2-Oxoacids regulate kynurenic acid production in the rat brain: studies in vitro and in vivo.Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate.Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats.
P2860
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P2860
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Presence of kynurenic acid in the mammalian brain.
@en
Presence of kynurenic acid in the mammalian brain.
@nl
type
label
Presence of kynurenic acid in the mammalian brain.
@en
Presence of kynurenic acid in the mammalian brain.
@nl
prefLabel
Presence of kynurenic acid in the mammalian brain.
@en
Presence of kynurenic acid in the mammalian brain.
@nl
P2093
P1476
Presence of kynurenic acid in the mammalian brain.
@en
P2093
P304
P356
10.1111/J.1471-4159.1988.TB04852.X
P407
P577
1988-07-01T00:00:00Z