Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
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Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolutionMolecular targets for antiepileptic drug developmentPlasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic BrainMechanisms of GABAergic homeostatic plasticityNeuronal morphology goes digital: a research hub for cellular and system neuroscienceCortical HCN channels: function, trafficking and plasticityAcute alterations of somatodendritic action potential dynamics in hippocampal CA1 pyramidal cells after kainate-induced status epilepticus in miceIon channels in genetic and acquired forms of epilepsy.Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialEnhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampusDifferential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampusActivity-dependent heteromerization of the hyperpolarization-activated, cyclic-nucleotide gated (HCN) channels: role of N-linked glycosylationLocalization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturationAmygdalocortical circuitry in schizophrenia: from circuits to molecules.Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy.Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.Epileptogenesis provoked by prolonged experimental febrile seizures: mechanisms and biomarkers.Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsySub region-specific modulation of synchronous neuronal burst firing after a kainic acid insult in organotypic hippocampal cultures.Epileptogenesis in the immature brain: emerging mechanisms.A selective interplay between aberrant EPSPKA and INaP reduces spike timing precision in dentate granule cells of epileptic rats.Dendritic ion channel trafficking and plasticity.Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysisThe effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat.Alterations in hyperpolarization-activated cyclic nucleotidegated cation channel (HCN) expression in the hippocampus following pilocarpine-induced status epilepticus.Mossy fiber plasticity and enhanced hippocampal excitability, without hippocampal cell loss or altered neurogenesis, in an animal model of prolonged febrile seizuresFormation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures.Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction.Calcium store depletion induces persistent perisomatic increases in the functional density of h channels in hippocampal pyramidal neurons.Do seizures affect the developing brain? Lessons from the laboratory.Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice.Fever, febrile seizures and epilepsy.Altered intrinsic properties of neuronal subtypes in malformed epileptogenic cortex.Is neuronal death required for seizure-induced epileptogenesis in the immature brain?HCN channels in behavior and neurological disease: too hyper or not active enough?Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy.Quantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization-activated cyclic nucleotide-gated channels throughout development in rat hippocampus.I(h)-mediated depolarization enhances the temporal precision of neuronal integration.Epileptogenesis after prolonged febrile seizures: mechanisms, biomarkers and therapeutic opportunities.
P2860
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P2860
Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Persistently modified h-channe ...... nhibition to hyperexcitability
@en
Persistently modified h-channe ...... nhibition to hyperexcitability
@nl
type
label
Persistently modified h-channe ...... nhibition to hyperexcitability
@en
Persistently modified h-channe ...... nhibition to hyperexcitability
@nl
prefLabel
Persistently modified h-channe ...... nhibition to hyperexcitability
@en
Persistently modified h-channe ...... nhibition to hyperexcitability
@nl
P2093
P2860
P356
P1433
P1476
Persistently modified h-channe ...... nhibition to hyperexcitability
@en
P2093
P2860
P2888
P304
P356
10.1038/85480
P407
P577
2001-03-01T00:00:00Z