Mutational analysis of the membrane-proximal cleavage site of L-selectin: relaxed sequence specificity surrounding the cleavage site.
about
Transmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55Receptor tyrosine kinases in the nucleusStructural Insights into Calmodulin-regulated L-selectin Ectodomain SheddingAn activated L-selectin mutant with conserved equilibrium binding properties but enhanced ligand recognition under shear flowAutolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activityShedding of Collagen XVII/BP180: STRUCTURAL MOTIFS INFLUENCE CLEAVAGE FROM CELL SURFACEL-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10Towards an understanding of the molecular basis of immune responses in sponges: the marine demosponge Geodia cydonium as a model.ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis.Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937.Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface.Molecular and cellular mechanisms of ectodomain sheddingRole of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes.Trafficking of receptor tyrosine kinases to the nucleusThe role of protease activity in ErbB biology.Prevention of In vitro neutrophil adhesion to endothelial cells through shedding of L-selectin by C-reactive protein and peptides derived from C-reactive protein.Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-1 activity.Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process.Pro-tumor necrosis factor-alpha processing activity is tightly controlled by a component that does not affect notch processing.Membrane protein secretasesRecognition sequences and structural elements contribute to shedding susceptibility of membrane proteins.ADAM-17-independent shedding of L-selectin.Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins.Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertase.EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment.Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPalpha pathway in primates.Differential effects of hydroxamate inhibitors on PMA and ligand-induced L-Selectin down-modulation: role of membrane proximal and cytoplasmic domains.A head-to-tail view of L-selectin and its impact on neutrophil behaviour.Mutational suppression of transferrin receptor shedding can be compensated by distinct metalloproteases acting on alternative sites.Role of Metalloproteases in the Release of the IL-1 type II Decoy ReceptorRole of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding
P2860
Q24595955-2C22B3ED-8C70-439A-8068-BA9328C8FB49Q26830216-1D5BF78D-4651-410D-B554-DC76A6165020Q27681231-7673ED84-27DA-43DB-B6D2-444A2582F43AQ28117130-A6948AB5-770E-4E5D-9F3A-1C12E5CE7D33Q28209976-0F647109-93AC-4276-8D64-E1CC697CDA53Q29013483-305015FA-8AA4-46AD-A94A-4AE96234BAD9Q30633203-8CF58105-72D5-4737-8FE0-91CD776D6824Q33498106-12015791-08DF-4B1B-979D-397091A3EDA2Q33547023-3E0D1AFA-6E4E-47C0-80E6-9636A17DC791Q33805782-B8E4BE96-69E9-42B3-826A-4BD1B37F6551Q35045668-EEA823E7-A99C-4961-823D-AABF07F276BAQ35340703-4F57533F-34D8-43C8-A3BD-221C6631D1F5Q35588890-FBB96A7A-B7DC-419E-B418-C2B87B784195Q35616136-DE187A91-0341-4C21-8E0A-2AD386F395D5Q35669580-0829E6EB-5B69-486B-A64A-6325711AF24FQ36210626-8537114C-790C-4664-8F20-9EFFE726C545Q36255902-F5F8803A-9703-4F4B-B4DE-0FA786D65D2DQ36371875-8A3F8A4C-AAB0-4F18-83A7-AC7A1431677BQ37308472-76B12EAE-C389-4363-B119-5E6DDB29B62DQ37326973-B9AC2438-2030-44A4-8FC7-82ECC9A17F8EQ37370255-45F0EF62-B7F0-49AA-8E09-DDF9D486E7F6Q37743354-E6CE6548-206E-4B8F-B692-5B446C6E475AQ38293570-CB1D2F00-290B-4949-B5EB-29FA184E3B65Q38734413-3D76347E-EFC5-4D7F-B3AE-697808BD492AQ40704613-E04CF769-0B52-4AD5-8D8D-6B5A6AB8ED90Q41009791-2C92667B-55C6-488F-BCB3-C5110430DD94Q41341215-45753EE8-2E71-4F95-B16E-8757E31632A1Q42074336-1AC5EEE1-1EC0-4838-816D-90458452B1A4Q42446882-A6B5E754-5479-45FF-AF73-CA4873B2AD8BQ42487291-32EA6A63-A363-4430-B77F-76226D9AA1F0Q43559838-171AABB4-6032-44ED-B5A8-05EE7AB5578BQ44121118-E5B1D34D-BDED-4B80-A985-6BE03F78E8A7Q44517519-8E828331-20B3-4E41-BDB3-0EDCEF9C8247Q45221632-B26C3245-56D4-41AB-9D53-9BE616CF2AB7Q47910010-E90AF297-DFF6-4C0F-A938-7652C42519D7Q49898832-8F9FA470-78F5-4DFE-B753-49CD662009ADQ51839290-81BE291A-742D-4D6C-9F22-6C7B5B0B586BQ56943427-61A3954D-2B49-4161-9BB9-D59182381866Q58000959-F7819934-2459-4E7B-BB98-5AB5E73783BB
P2860
Mutational analysis of the membrane-proximal cleavage site of L-selectin: relaxed sequence specificity surrounding the cleavage site.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Mutational analysis of the mem ...... surrounding the cleavage site.
@en
Mutational analysis of the mem ...... surrounding the cleavage site.
@nl
type
label
Mutational analysis of the mem ...... surrounding the cleavage site.
@en
Mutational analysis of the mem ...... surrounding the cleavage site.
@nl
prefLabel
Mutational analysis of the mem ...... surrounding the cleavage site.
@en
Mutational analysis of the mem ...... surrounding the cleavage site.
@nl
P2093
P2860
P356
P1476
Mutational analysis of the mem ...... surrounding the cleavage site.
@en
P2093
P2860
P304
P356
10.1084/JEM.182.2.549
P407
P577
1995-08-01T00:00:00Z