In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine.
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THC Prevents MDMA Neurotoxicity in MiceToxicity of amphetamines: an updateLost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humansThe pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to ratsThe mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brainIn vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMAVascular actions of MDMA involve alpha1 and alpha2-adrenoceptors in the anaesthetized ratA study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brainNon-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma CellsEcstasy: are animal data consistent between species and can they translate to humans?Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.Developmental effects of 3,4-methylenedioxymethamphetamine: a reviewp-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.Withanolide A prevents neurodegeneration by modulating hippocampal glutathione biosynthesis during hypoxia.The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.Sleep deprivation differentially impairs cognitive performance in abstinent methylenedioxymethamphetamine ("Ecstasy") users.Mitochondria: key players in the neurotoxic effects of amphetamines.Causes and consequences of methamphetamine and MDMA toxicity.Effect of repeated exposure to MDMA on the function of the 5-HT transporter as assessed by synaptosomal 5-HT uptake.Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons.Chronic unpredictable stress augments +3,4-methylenedioxymethamphetamine-induced monoamine depletions: the role of corticosteroneHydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice.Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates.The role of dopamine receptors in the neurotoxicity of methamphetamine.MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature.Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia.Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA.Investigation of the prejunctional alpha2-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens.Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity.Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures.MDMA induces caspase-3 activation in the limbic system but not in striatum.A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice.Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine ('ecstasy')-induced dopamine release and free radical formation in the mouse striatum.Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats.The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice.Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.Effects of antihistamines on fenfluramine-induced depletion of indoles in the brain of rats.Evidence for a role of Hsp70 in the neuroprotection induced by heat shock pre-treatment against 3,4-methylenedioxymethamphetamine toxicity in rat brain.Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain.
P2860
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P2860
In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
In vivo evidence for free radi ...... ration following fenfluramine.
@en
In vivo evidence for free radi ...... llowing administration of MDMA
@nl
type
label
In vivo evidence for free radi ...... ration following fenfluramine.
@en
In vivo evidence for free radi ...... llowing administration of MDMA
@nl
prefLabel
In vivo evidence for free radi ...... ration following fenfluramine.
@en
In vivo evidence for free radi ...... llowing administration of MDMA
@nl
P2093
P2860
P356
P1476
In vivo evidence for free radi ...... ration following fenfluramine.
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0701213
P407
P577
1997-07-01T00:00:00Z