Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations
about
Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionDetecting low frequent loss-of-function alleles in genome wide association studies with red hair color as exampleGenetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles.Multiple regression methods show great potential for rare variant association tests.Complete effect-profile assessment in association studies with multiple genetic and multiple environmental factors.Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regressionSTABILITY and SOLID-TIMI 52: Lipoprotein associated phospholipase A2 (Lp-PLA2) as a biomarker or risk factor for cardiovascular diseases.Biallelic mutations in PLA2G5, encoding group V phospholipase A2, cause benign fleck retinaRare Variants Association Analysis in Large-Scale Sequencing Studies at the Single Locus LevelModulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2Meta-Analysis of Rare Variant Association Tests in Multiethnic Populations.Empirical power of very rare variants for common traits and disease: results from sanger sequencing 1998 individuals.Testing for modes of inheritance involving compound heterozygotes.DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development.On the substructure controls in rare variant analysis: Principal components or variance components?Re-examining Dis/Similarity-Based Tests for Rare-Variant Association with Case-Control Samples.
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P2860
Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
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2011年论文
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name
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@en
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@nl
type
label
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@en
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@nl
prefLabel
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@en
Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@nl
P2093
P2860
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Sequencing of Lp-PLA2-encoding ...... are loss-of-function mutations
@en
P2093
D M Waterworth
J C Whittaker
M R Nelson
S-A Bacanu
V E Mooser
P2860
P2888
P304
P356
10.1038/TPJ.2011.20
P577
2011-05-24T00:00:00Z
P5875
P6179
1040370126