Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
about
High-affinity human PD-L1 variants attenuate the suppression of T cell activation.Inhibition of the checkpoint protein PD-1 by the therapeutic antibody pembrolizumab outlined by quantum chemistry.Molecular dynamics simulations elucidate conformational selection and induced fit mechanisms in the binding of PD-1 and PD-L1.High-affinity PD-1 molecules deliver improved interaction with PD-L1 and PD-L2
P2860
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@en
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@nl
type
label
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@en
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@nl
prefLabel
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@en
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@nl
P2093
P2860
P1433
P1476
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
@en
P2093
Andrew C Kruse
Gregory R Bowman
Joseph Kao
Roberta Pascolutti
Roy L Maute
Xianqiang Sun
P2860
P304
P356
10.1016/J.STR.2016.06.026
P50
P577
2016-09-07T00:00:00Z