about
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15Activation and allosteric modulation of a muscarinic acetylcholine receptorEngineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies.Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathwayAdrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobodyMolecular physiology of the WNK kinases.Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.Cytokine therapy reverses NK cell anergy in MHC-deficient tumors"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosisAntibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.Practical Immuno-PET Radiotracer Design Considerations for Human Immune Checkpoint Imaging.Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants.Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20.T cells expressing chimeric antigen receptor promote immune tolerance.Yeast surface display platform for rapid discovery of conformationally selective nanobodies.Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host PhysiologyGDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance
P50
Q24301975-255332DD-E0E7-4213-83F4-1851BB1FC7A6Q24308061-B8A316D6-5A76-47DA-AB6E-EE3E92C97D35Q24605057-0EEBD19B-AD22-4D66-BF23-2FEE50F6EA01Q24648927-1ACC516E-B0F3-427E-BDB8-0EEEE815FC55Q27680016-AD17B014-C459-45C1-8CDB-9F10BE899330Q31134261-6272564C-2AA8-4B68-A7E3-49FB3DD799E5Q34651528-30401A13-F38F-4BE8-8274-D1BD679FFB4AQ35140125-80BF902C-7B63-45D4-8756-885ADC4C75FFQ35608098-1AF98435-BBC2-4B9D-8CE6-556CF133416AQ35630914-7DEB94F9-886E-4BF7-B55A-3033DFBDE42BQ35651892-0F791230-8D43-4E14-8D1F-0B604A82D838Q36028807-3229B690-411F-42E1-B56F-CE91EBAFA9E0Q37042256-33FFFBD2-114F-496F-8A18-36E47B9296ACQ38703214-E2BACABB-273E-4E35-9A98-AD503A65B133Q38726053-E0B27F9B-B696-47A0-9036-96CBFD94C197Q42087195-CF5BBAD8-9414-4595-B65A-019AF66598B3Q42387009-F7EE974F-7A86-494F-85DB-4FF4C561F5E4Q45033916-29CD7A68-7B42-4D6E-A589-DC98081A675DQ46045077-9C67AEB7-DF56-4750-96AD-32754ECF21A8Q50055169-1085ACE7-AACC-497D-9F34-F4FC7BBECC35Q50963822-8D771D57-6118-4BB9-B0E3-7C7243C6E1B5Q90047479-BDB374B1-21C3-4D27-9EF2-322A53FA8AB0Q92551402-66A5C21E-7224-4C81-915C-EEE309CA1D5A
P50
description
researcher ORCID ID = 0000-0003-3699-2446
@en
wetenschapper
@nl
name
Aaron Ring
@ast
Aaron Ring
@en
Aaron Ring
@es
Aaron Ring
@nl
type
label
Aaron Ring
@ast
Aaron Ring
@en
Aaron Ring
@es
Aaron Ring
@nl
prefLabel
Aaron Ring
@ast
Aaron Ring
@en
Aaron Ring
@es
Aaron Ring
@nl
P106
P21
P31
P496
0000-0003-3699-2446