Aromatic Nonpolar Nucleosides as Hydrophobic Isosteres of Pyrimidine and Purine Nucleosides.
about
Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase IPairing Geometry of the Hydrophobic Thymine Analogue 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray CrystallographyProbing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-ray Crystallography and Non-Hydrogen Bonding Isosteric Base AnaloguesHydrogen-Bonding Capability of a Templating Difluorotoluene Nucleotide Residue in an RB69 DNA Polymerase Ternary ComplexProbing Minor Groove Hydrogen Bonding Interactions between RB69 DNA Polymerase and DNASolution structure of a DNA duplex containing a replicable difluorotoluene-adenine pairSyntheses of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-dihydroxy-2-propoxy)methyl]- derivatives of 5-substituted-2,4-difluorobenzene: unnatural acyclo thymidine mimics for evaluation as anticancer and antiviral agents.RB69 DNA polymerase structure, kinetics, and fidelity.C-Nucleosides Derived from Simple Aromatic HydrocarbonsEvidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappaDifluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication.Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson-Crick Hydrogen Bonds?Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for DeoxyadenosineSelective and Stable DNA Base Pairing without Hydrogen Bonds.Naphthalene, Phenanthrene, and Pyrene as DNA Base Analogues: Synthesis, Structure, and Fluorescence in DNA.Factors Contributing to Aromatic Stacking in Water: Evaluation in the Context of DNA.Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA.Highly Precise Shape Mimicry by a Difluorotoluene Deoxynucleoside, a Replication-Competent Substitute for Thymidine.Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes.Formation of Stable DNA Loops by Incorporation of Nonpolar, Non-Hydrogen-Bonding Nucleoside Isosteres.Experimental Measurement of Aromatic Stacking Affinities in the Context of Duplex DNASurvey and summary: The applications of universal DNA base analoguesStructure and replication of yDNA: a novel genetic set widened by benzo-homologationQuantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis.NDI and DAN DNA: nucleic acid-directed assembly of NDI and DAN.High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds.Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta.Measurement and theory of hydrogen bonding contribution to isosteric DNA base pairs.Expanding the horizon of the thymine isostere biochemistry: unique cyclobutane dimers formed by photoreaction between a thymine and a toluene residue in the dinucleotide framework.Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity.Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection.A thymidine triphosphate shape analog lacking Watson-Crick pairing ability is replicated with high sequence selectivity.The difluorotoluene debate--a decade later.Steric and electrostatic effects in DNA synthesis by the SOS-induced DNA polymerases II and IV of Escherichia coli.Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base.Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic setsA sequential indium-mediated aldehyde allylation/palladium-catalyzed cross-coupling reaction in the synthesis of 2-deoxy-beta-C-aryl glycosides.Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications.Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase.Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs.
P2860
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P2860
Aromatic Nonpolar Nucleosides as Hydrophobic Isosteres of Pyrimidine and Purine Nucleosides.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@en
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@nl
type
label
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@en
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@nl
prefLabel
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@en
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@nl
P2860
P356
P1476
Aromatic Nonpolar Nucleosides ...... midine and Purine Nucleosides.
@en
P2093
Barbara A Schweitzer
Eric T Kool
P2860
P304
P356
10.1021/JO00103A013
P407
P577
1994-12-01T00:00:00Z