Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly
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Adeno-associated Virus as a Mammalian DNA VectorStructure of Adeno-Associated Virus Serotype 8, a Gene Therapy VectorThe structure of AAVrh32.33, a novel gene delivery vectorStructure of neurotropic adeno-associated virus AAVrh.8.Sequence Conservation, Radial Distance and Packing Density in Spherical Viral Capsids.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network.Comparative analysis of adeno-associated virus capsid stability and dynamicsRecombination and population mosaic of a multifunctional viral gene, adeno-associated virus cap.DNA shuffling of adeno-associated virus yields functionally diverse viral progenyThe role of nuclear localization signal in parvovirus life cycle.Classic nuclear localization signals and a novel nuclear localization motif are required for nuclear transport of porcine parvovirus capsid proteins.Adeno-associated virus: a key to the human genome?Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.Intracellular transport of recombinant adeno-associated virus vectors.Modeling the step of endosomal escape during cell infection by a nonenveloped virusIn Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy VectorMapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8.Super-resolution imaging of nuclear import of adeno-associated virus in live cells.Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction.Adeno-associated virus capsid antigen presentation is dependent on endosomal escape.Surface loop dynamics in adeno-associated virus capsid assembly.Disruption of Microtubules Post-Virus Entry Enhances Adeno-Associated Virus Vector Transduction.Recombinant adeno-associated virus transduction and integration.Capsid antibodies to different adeno-associated virus serotypes bind common regions.Parvovirus B19 uptake is a highly selective process controlled by VP1u, a novel determinant of viral tropism.Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors.Recombinant adeno-associated virus utilizes host cell nuclear import machinery to enter the nucleusAdeno-associated virus structural biology as a tool in vector development.Nuclear entry of DNA viruses.Adeno-Associated Virus Vectors and Stem Cells: Friends or Foes?Cellular transduction mechanisms of adeno-associated viral vectors.Biomaterial-Guided Gene Delivery for Musculoskeletal Tissue Repair.Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.Impact of VP1-specific protein sequence motifs on adeno-associated virus type 2 intracellular trafficking and nuclear entry.Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates.Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells.Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions.Adeno-associated virus capsid proteins may play a role in transcription and second-strand synthesis of recombinant genomes
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P2860
Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Separate basic region motifs w ...... l for infectivity and assembly
@en
Separate basic region motifs w ...... l for infectivity and assembly
@nl
type
label
Separate basic region motifs w ...... l for infectivity and assembly
@en
Separate basic region motifs w ...... l for infectivity and assembly
@nl
prefLabel
Separate basic region motifs w ...... l for infectivity and assembly
@en
Separate basic region motifs w ...... l for infectivity and assembly
@nl
P2093
P2860
P356
P1433
P1476
Separate basic region motifs w ...... l for infectivity and assembly
@en
P2093
Joshua C Grieger
Richard J Samulski
Stephen Snowdy
P2860
P304
P356
10.1128/JVI.02723-05
P407
P577
2006-06-01T00:00:00Z