Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus. - Wikidata - awgldk - TriplyDB

Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.

Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.

http://www.wikidata.org/entity/Q39306165

about

Adeno-associated Virus as a Mammalian DNA Vector Role of capsid proteins in parvoviruses infection Virus strategies for passing the nuclear envelope barrier Parvoviruses cause nuclear envelope breakdown by activating key enzymes of mitosis Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking Electron microscopy analysis of a disaccharide analog complex reveals receptor interactions of adeno-associated virus The structure of AAVrh32.33, a novel gene delivery vector Structure of neurotropic adeno-associated virus AAVrh.8.Sequence Conservation, Radial Distance and Packing Density in Spherical Viral Capsids.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues.Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network.Comparative analysis of adeno-associated virus capsid stability and dynamics Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.Recombination and population mosaic of a multifunctional viral gene, adeno-associated virus cap.In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses.Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity.Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.Parvovirus particles and movement in the cellular cytoplasm and effects of the cytoskeleton.The globoside receptor triggers structural changes in the B19 virus capsid that facilitate virus internalization Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.Nuclear envelope disruption involving host caspases plays a role in the parvovirus replication cycle.Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides Mutations at the base of the icosahedral five-fold cylinders of minute virus of mice induce 3'-to-5' genome uncoating and critically impair entry functions.Intracellular transport of recombinant adeno-associated virus vectors.Tyrosine cross-linking reveals interfacial dynamics in adeno-associated viral capsids during infection Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8.Survival and Intra-Nuclear Trafficking of Burkholderia pseudomallei: Strategies of Evasion from Immune Surveillance?Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection.Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy Parvovirus diversity and DNA damage responses Adeno-associated virus capsid antigen presentation is dependent on endosomal escape.Surface loop dynamics in adeno-associated virus capsid assembly.Disruption of Microtubules Post-Virus Entry Enhances Adeno-Associated Virus Vector Transduction.Ultrasound targeted microbubble destruction stimulates cellular endocytosis in facilitation of adeno-associated virus delivery.Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles Recombinant adeno-associated virus transduction and integration.

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P2860

Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.

http://www.wikidata.org/entity/Q39306165

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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2006年學術文章

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name

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

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Adeno-associated virus type 2 ...... coating occurs in the nucleus.

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type

label

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

@en

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

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prefLabel

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

@en

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

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P1433

Journal of Virology

P1476

Adeno-associated virus type 2 ...... coating occurs in the nucleus.

@en

P2093

Barbara Leuchs

http://www.w3.org/2001/XMLSchema#string

Florian Sonntag

http://www.w3.org/2001/XMLSchema#string

Jürgen A Kleinschmidt

http://www.w3.org/2001/XMLSchema#string

Roger Fischer

http://www.w3.org/2001/XMLSchema#string

Svenja Bleker

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P2860

How Viruses Enter Animal Cells

Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism.

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps.

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells.

Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein

Nucleocytoplasmic transport: the soluble phase

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

Virus entry: open sesame

P304

11040-11054

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scholarly article

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10.1128/JVI.01056-06

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P407

P433

22

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P478

80

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P577

2006-09-06T00:00:00Z

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16956943

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P932

1642181

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