about
Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperaturesCrystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitorsCrystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogueRefined structure of Pyrococcus furiosus ornithine carbamoyltransferase at 1.87 ADetermination of Kinetics and the Crystal Structure of a Novel Type 2 Isopentenyl Diphosphate: Dimethylallyl Diphosphate Isomerase fromStreptococcus pneumoniaeCrystal structure of a cold-adapted class C beta-lactamaseMonoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystalsProtecting role of cosolvents in protein denaturation by SDS: a structural studySynthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomeraseStructural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3BTargeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of FosmidomycinSynthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one coreOverproduced Brucella abortus PdhS-mCherry forms soluble aggregates in Escherichia coli, partially associating with mobile foci of IbpA-YFP.Structural analysis of Brucella abortus RicA substitutions that do not impair interaction with human Rab2 GTPase.Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB(1) cannabinoid receptor ligands and potential antagonists: synthesis, lipophilicity, affinity, and molecular modeling.Purification, cloning, and three-dimensional structure prediction of Micrococcus luteus FAD-containing tyramine oxidase.A selective calix[6]arene-based fluorescent chemosensor for phosphatidylcholine type lipids.Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation.Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors.Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesisAnalysis of conserved active site residues in monoamine oxidase A and B and their three-dimensional molecular modelingA reversible monoamine oxidase A inhibitor, befloxatone: structural approach of its mechanism of action.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenaseendo-3,3-Dimethyl-4-oxobicyclo-[3.1.0]hexan-2-yl methane-sulfonate.Phenyl 2,3,4-tri-O-benzyl-1-thio-α-d-mannopyran-oside monohydrateChemoresistance to Valproate Treatment of Bovine Leukemia Virus-Infected Sheep; Identification of Improved HDAC Inhibitors.4-Nitro-N-phthalyl-l-tryptophan.Modeling of human monoamine oxidase A: from low resolution threading models to accurate comparative models based on crystal structures.A nano-sized container for specific encapsulation of isolated water molecules.Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes.Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.Solid-state-trapped reactive ammonium carbamate self-derivative salts of prolinamide.A review on the monoacylglycerol lipase: at the interface between fat and endocannabinoid signalling.Pharmaceutical salts and cocrystals involving amino acids: a brief structural overview of the state-of-art.Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors.A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis.Preparation and characterization of a new harmine-based antiproliferative compound in complex with cyclodextrin: Increasing solubility while maintaining biological activity.3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties.Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Johan Wouters
@ast
Johan Wouters
@en
Johan Wouters
@es
Johan Wouters
@nl
Johan Wouters
@sl
type
label
Johan Wouters
@ast
Johan Wouters
@en
Johan Wouters
@es
Johan Wouters
@nl
Johan Wouters
@sl
prefLabel
Johan Wouters
@ast
Johan Wouters
@en
Johan Wouters
@es
Johan Wouters
@nl
Johan Wouters
@sl
P106
P1153
7102732070
P21
P31
P496
0000-0002-4920-6857