p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair.
about
p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loopInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)p53 in the DNA-Damage-Repair ProcessThe interaction of p53 with replication protein A mediates suppression of homologous recombinationATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damagep53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation.p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.p53 differentially inhibits cell growth depending on the mechanism of telomere maintenanceDissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants.p53 Monitors replication fork regression by binding to "chickenfoot" intermediates.p73 coordinates with Δ133p53 to promote DNA double-strand break repair.
P2860
Q24548984-CF89ACF8-2AC7-4A3A-B909-BBA99D22B9F4Q27002581-CBCF1DE2-D25E-433D-B282-335C1AEE939DQ28073944-E511FF73-5DD0-4E7C-ABD0-94839D497EF2Q28288360-775A97D2-AB2B-441B-92EF-19DD34DBBEC0Q31029673-E7FA1DBA-3797-413E-8144-A630E151701AQ33350162-172D610D-066F-4C99-93B2-3C8C50DE6880Q35146231-8FBE51B1-F2C2-4B7E-997A-809CBC595256Q39367978-F7D47FB6-CB48-4CEC-AC8A-F3709476B723Q40344795-451ACE97-58E5-4CE1-AAE1-9C516E3C016CQ40544871-4493C55F-8DA3-46FF-BD4D-554773D4D3C1Q42433750-7D1396C5-9893-46B4-A207-401F80B59E0BQ52661409-F843E3E8-E6FA-494F-A089-950B4598EE2AQ52671036-4A48F35B-4C60-46A3-9D8F-541412112FDC
P2860
p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
p53 mutated in the transactiva ...... ed double-strand break repair.
@en
p53 mutated in the transactiva ...... ed double-strand break repair.
@nl
type
label
p53 mutated in the transactiva ...... ed double-strand break repair.
@en
p53 mutated in the transactiva ...... ed double-strand break repair.
@nl
prefLabel
p53 mutated in the transactiva ...... ed double-strand break repair.
@en
p53 mutated in the transactiva ...... ed double-strand break repair.
@nl
P2093
P2860
P356
P1433
P1476
p53 mutated in the transactiva ...... ed double-strand break repair.
@en
P2093
Gisa S Boehden
Klaus Roemer
Lisa Wiesmüller
Nuray Akyüz
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206632
P407
P577
2003-06-01T00:00:00Z
P5875
P6179
1031893716