Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms.
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NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrinIdentification of a mitochondrial Na+/H+ exchangerCoexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3.Phosphorylation of Ser(982) in the sodium bicarbonate cotransporter kNBC1 shifts the HCO(3)(-) : Na(+) stoichiometry from 3 : 1 to 2 : 1 in murine proximal tubule cellsMolecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cellsMolecular mechanisms and regulation of urinary acidificationRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsEzrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interactionClathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeletonShank2 associates with and regulates Na+/H+ exchanger 3Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranesAT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension.Gastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border.Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1A-NHE3 pathway: implications in renal tubular pathobiology.NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.The expanding family of eucaryotic Na(+)/H(+) exchangers.Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin.cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor.Luminal Na(+)/H (+) exchange in the proximal tubuleSignal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA.Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry.Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo.Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2.Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3Human intestinal epithelial cell line SK-CO15 is a new model system to study Na(+)/H(+) exchanger 3Secretory diarrhoea: mechanisms and emerging therapies.Membrane topology of NHE3. Epitopes within the carboxyl-terminal hydrophilic domain are exoplasmic.Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF)Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3Regulation of intestinal electroneutral sodium absorption and the brush border Na+/H+ exchanger by intracellular calcium.Na+/H+ exchangers.Angiotensin II counteracts the effects of cAMP/PKA on NHE3 activity and phosphorylation in proximal tubule cells.Fructose acutely stimulates NHE3 activity in kidney proximal tubule.Physiological and molecular analysis of acid loading mechanisms in squamous and columnar-lined esophagus.Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites.
P2860
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P2860
Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Identification of sites requir ...... t and -independent mechanisms.
@en
Identification of sites requir ...... t and -independent mechanisms.
@nl
type
label
Identification of sites requir ...... t and -independent mechanisms.
@en
Identification of sites requir ...... t and -independent mechanisms.
@nl
prefLabel
Identification of sites requir ...... t and -independent mechanisms.
@en
Identification of sites requir ...... t and -independent mechanisms.
@nl
P2093
P2860
P356
P1476
Identification of sites requir ...... t and -independent mechanisms.
@en
P2093
P2860
P304
28672-28679
P356
10.1074/JBC.272.45.28672
P407
P577
1997-11-01T00:00:00Z