Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
about
The PHR proteins: intracellular signaling hubs in neuronal development and axon degenerationZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonatesOpposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLKLeucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells.TNFα-induced DLK activation contributes to apoptosis in the beta-cell line HIT.Dual leucine zipper kinase (MAP3K12) modulators: a patent review (2010-2015).Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration.Intrinsic mechanisms for axon regeneration: insights from injured axons in Drosophila.Roles of palmitoylation in axon growth, degeneration and regeneration.Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicityRestraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104.Pathological axonal death through a MAPK cascade that triggers a local energy deficit.Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death.Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury.
P2860
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P2860
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@en
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@nl
type
label
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@en
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@nl
prefLabel
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@en
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@nl
P2093
P2860
P356
P1476
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
@en
P2093
Adrian M Jubb
Alvin Gogineni
Arundhati Sengupta Ghosh
Christine D Pozniak
Daisy Bustos
Gai Ayalon
Hilda Solanoy
Jesse E Hanson
P2860
P304
P356
10.1084/JEM.20122832
P407
P577
2013-10-28T00:00:00Z