A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
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Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal diseaseNeonatal diabetes: an expanding list of genes allows for improved diagnosis and treatmentGenetics and pathophysiology of neonatal diabetes mellitus.Transcription factor regulation of pancreatic organogenesis, differentiation and maturationIdentification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2)GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimTRANSCRIPTION FACTOR GLI-SIMILAR 3 (GLIS3): IMPLICATIONS FOR THE DEVELOPMENT OF CONGENITAL HYPOTHYROIDISM.Revealing transcription factors during human pancreatic β cell development.Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.4D MRI of polycystic kidneys from rapamycin-treated Glis3-deficient miceSUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal CellsGlis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6.Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults.Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription.Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease.Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man.Viral suppression of RNA silencing.Pancreatic islet cell development and regeneration.The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers.Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis.Glis family proteins are differentially implicated in the cellular reprogramming of human somatic cells.Zinc-finger proteins in health and disease.GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.GLIS1-3: emerging roles in reprogramming, stem and progenitor cell differentiation and maintenance.GLIS3 rs7020673 and rs10758593 polymorphisms interact in the susceptibility for type 1 diabetes mellitus.Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes
P2860
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P2860
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@en
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@nl
type
label
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@en
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@nl
prefLabel
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@en
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@nl
P2093
P2860
P1433
P1476
A murine model of neonatal diabetes mellitus in Glis3-deficient mice.
@en
P2093
Hiroshi Kiyonari
Hisashi Hashimoto
Kaoru Yasuda
Kentaro Hiramatsu
Naoki Watanabe
Naoko Oshima
Norihiko Suzuki
Rieko Miyamoto
Saori Nishio
P2860
P304
P356
10.1016/J.FEBSLET.2009.05.039
P407
P577
2009-05-28T00:00:00Z