Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice - Wikidata - awgldk - TriplyDB

Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

http://www.wikidata.org/entity/Q42458205

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Imaging of Leukocyte Trafficking in Alzheimer's Disease Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease.Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue - Evaluations on Monocyte-Based Delivery System for the Central Nervous System Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat Stepping back to move forward: a current review of iPSCs in the fight against Alzheimer's disease β-amyloid, microglia, and the inflammasome in Alzheimer's disease Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice.How to get from here to there: macrophage recruitment in Alzheimer's disease Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer's disease.Toll-like receptor 4 is a regulator of monocyte and electroencephalographic responses to sleep loss.Intravenous infusion of monocytes isolated from 2-week-old mice enhances clearance of Beta-amyloid plaques in an Alzheimer mouse model Platelets in the Alzheimer's disease brain: do they play a role in cerebral amyloid angiopathy?Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells.Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking.MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease.Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain.Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment Genetic therapy for the nervous system.Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications.Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer 'if' but 'how'.Stem-cell challenges in the treatment of Alzheimer's disease: a long way from bench to bedside.Migration of blood cells to β-amyloid plaques in Alzheimer's disease.Engineering Stem Cells for Biomedical Applications.Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.Viral vectors for therapy of neurologic diseases.Friend or Foe? Resident Microglia vs Bone Marrow-Derived Microglia and Their Roles in the Retinal Degeneration.Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques.The generation of NGF-secreting primary rat monocytes: a comparison of different transfer methods.Inflammatory status of transmigrating primary rat monocytes in a novel perfusion model simulating blood flow.A role for spleen monocytes in post-ischemic brain inflammation and injury.Platelet-derived nerve growth factor supports the survival of cholinergic neurons in organotypic rat brain slices Hematopoietic CC-chemokine receptor 2 (CCR2) competent cells are protective for the cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.Animal Models of Alzheimer's Disease: Utilization of Transgenic Alzheimer's Disease Models in Studies of Amyloid Beta Clearance.

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Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

http://www.wikidata.org/entity/Q42458205

description

2010 nî lūn-bûn

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2010年论文

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2010年论文

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name

Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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type

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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JNEUROSCI.0329-10.2010

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Journal of Neuroscience

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Trafficking CD11b-positive blo ...... oid-depositing transgenic mice

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Chad A Dickey

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Daniel C Lee

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Dave Morgan

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Donna Herber

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John Koren

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Karoly Szekeres

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Kevin Nash

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Lori Lebson

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Marcia N Gordon

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Paul E Gottschall

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

Inflammation and Alzheimer's disease

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.

Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics.

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

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10.1523/JNEUROSCI.0329-10.2010

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29

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2010-07-01T00:00:00Z

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45365853

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20660248

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2929651

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