Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse - Wikidata - awgldk - TriplyDB

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

http://www.wikidata.org/entity/Q23917574

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Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.Complete morphologies of basal forebrain cholinergic neurons in the mouse.Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice Immunomodulation targeting abnormal protein conformation reduces pathology in a mouse model of Alzheimer's disease.17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice.Catecholaminergic neuronal loss in locus coeruleus of aged female dtg APP/PS1 mice.Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice.Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice.LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice Selective induction of calcineurin activity and signaling by oligomeric amyloid beta Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation.Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice.Functional recovery of cholinergic basal forebrain neurons under disease conditions: old problems, new solutions?Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.Immunotherapy for Alzheimer's disease.Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease.Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice Neurologic and motor dysfunctions in APP transgenic mice.Inflammatory changes parallel the early stages of Alzheimer disease.Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice.Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease.Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2.Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain.Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

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Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

http://www.wikidata.org/entity/Q23917574

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Time Course of the Development ...... oubly Transgenic PS1+APP Mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time Course of the Development ...... oubly Transgenic PS1+APP Mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time Course of the Development ...... oubly Transgenic PS1+APP Mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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Time course of the development ...... oubly transgenic PS1+APP mouse

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P1433

Experimental Neurology

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Time course of the development ...... oubly transgenic PS1+APP mouse

@en

P2093

Dave Morgan

http://www.w3.org/2001/XMLSchema#string

Donna Wilcock

http://www.w3.org/2001/XMLSchema#string

Giovanni DiCarlo

http://www.w3.org/2001/XMLSchema#string

Jason Melachrino

http://www.w3.org/2001/XMLSchema#string

Karen Connor

http://www.w3.org/2001/XMLSchema#string

Kristal W. Boyett

http://www.w3.org/2001/XMLSchema#string

Leigh A. Holcomb

http://www.w3.org/2001/XMLSchema#string

Marcia N. Gordon

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Paul T. Jantzen

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20023373

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183-195

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scholarly article

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10.1006/EXNR.2001.7754

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2

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173

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James P. O'Callaghan

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2002-02-01T00:00:00Z

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11537114

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11822882

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National Institute for Occupational Safety and Health

P921

Alzheimer's disease

neurological disorder