Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
about
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideAPLP2 Regulates Refractive Error and Myopia Development in Mice and HumansOrigins of amyloid-βAPP binds DR6 to trigger axon pruning and neuron death via distinct caspasesThe gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleusSox15 is required for skeletal muscle regenerationBinding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavageHomo- and heterodimerization of APP family members promotes intercellular adhesion.Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporterThe amyloid-beta precursor protein: integrating structure with biological functionImmunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseThe amyloid precursor protein: beyond amyloidModulation of statin-activated shedding of Alzheimer APP ectodomain by ROCKOctylphenol (OP) alters the expression of members of the amyloid protein family in the hypothalamus of the snapping turtle, Chelydra serpentina serpentinaSynapses and Alzheimer's diseaseGenetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesisAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresOverview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsThe Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain InjuryAmyloid Proteins and Their Role in Multiple Sclerosis. Considerations in the Use of Amyloid-PET ImagingThe Amyloid Precursor Protein-A Novel Player within the Molecular Array of Presynaptic NanomachinesCaenorhabditis elegans as a model organism to study APP functionInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseasePlatelets and Alzheimer's disease: Potential of APP as a biomarkerAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseThe Amyloid Precursor Protein Controls PIKfyve FunctionTailoring the antibody response to aggregated Aß using novel Alzheimer-vaccinesCrystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose OctasulfateCrystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerizationAPP processing in Alzheimer's diseaseRole of Drosophila Amyloid Precursor Protein in Memory FormationProteolytic processing of Alzheimer's β-amyloid precursor proteinIn vitro Pb exposure disturbs the balance between Aβ production and elimination: the role of AβPP and neprilysinIntracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegansCortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family membersAPP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsAPP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active ZoneAmyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers.
P2860
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P2860
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Mice with combined gene knock- ...... cursor protein family members.
@en
Mice with combined gene knock- ...... cursor protein family members.
@nl
type
label
Mice with combined gene knock- ...... cursor protein family members.
@en
Mice with combined gene knock- ...... cursor protein family members.
@nl
prefLabel
Mice with combined gene knock- ...... cursor protein family members.
@en
Mice with combined gene knock- ...... cursor protein family members.
@nl
P2093
P1476
Mice with combined gene knock- ...... ecursor protein family members
@en
P2093
C von Koch
D P Wolfer
H von Kretzschmar
J Hainfellner
P304
P356
10.1523/JNEUROSCI.20-21-07951.2000
P407
P577
2000-11-01T00:00:00Z