Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer. - Wikidata - awgldk - TriplyDB

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.

http://www.wikidata.org/entity/Q42508201

about

The Potential Role of Hedgehog Signaling in the Luminal/Basal Phenotype of Breast Epithelia and in Breast Cancer Invasion and Metastasis Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: pathological significance in early- and late-onset breast carcinoma.Pathway-BasedFeature Selection Algorithm for Cancer Microarray Data.Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland Prognostic significance of the methylation of Wnt pathway antagonists-CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling-ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas.Mammary development and breast cancer: the role of stem cells Hedgehog signaling in the normal and neoplastic mammary gland.Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Association of FANCC and PTCH1 with the development of early dysplastic lesions of the head and neck.Epigenetic heredity of human height.Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci.Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.Assessing combined methylation-sensitive high resolution melting and pyrosequencing for the analysis of heterogeneous DNA methylation Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells--interaction of hedgehog-gli and estrogen receptor signaling pathways.A seven-gene CpG-island methylation panel predicts breast cancer progression Shared signaling pathways in normal and breast cancer stem cells.Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis.Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells.Implications of hedgehog signaling antagonists for cancer therapy.The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy.In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.Development of mammary tumors by conditional expression of GLI1 Hedgehog signalling in breast cancer.Methylation of PTCH1a gene in a subset of gastric cancers Epigenetics and dermatological disease.The Hedgehog signalling pathway as a therapeutic target in early breast cancer development.Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.Hedgehog signaling in the liver.miR-212 promotes pancreatic cancer cell growth and invasion by targeting the hedgehog signaling pathway receptor patched-1.Detection and analysis of the methylation status of PTCH1 gene involved in the hedgehog signaling pathway in a human gastric cancer cell line.Comparison of PTCH1, COX-2, p53, and Ki-67 protein expression in basal cell carcinomas of nodular and superficial subtypes arising on the head and trunk.Co-activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer.Blocking the hedgehog pathway inhibits hepatoblastoma growth.The role of the Hedgehog signaling pathway in cancer: A comprehensive review.Downregulation of the hedgehog receptor PTCH1 in colorectal serrated adenocarcinomas is not caused by PTCH1 mutations.

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P2860

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.

http://www.wikidata.org/entity/Q42508201

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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type

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Breast Cancer Research and Treatment

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Unmasking of epigenetically si ...... sion of PTCH in breast cancer.

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Beth Y Karlan

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Bryan T Lin

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Elizabeth A Williamson

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H Phillip Koeffler

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Ido Wolf

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Julian C Desmond

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Shikha Bose

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P2860

Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.

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