Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.
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Genetic predictors of interindividual variability in hepatic CYP3A4 expressionRole of pregnane X receptor in chemotherapeutic treatmentPharmacogenomics and personalized medicine: a review focused on their application in the Chinese populationCYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, HaitiPolymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination.The PXR rs7643645 polymorphism is associated with the risk of higher prostate-specific antigen levels in prostate cancer patientsPXR variants and artemisinin use in Vietnamese subjects: frequency distribution and impact on the interindividual variability of CYP3A induction by artemisininPopulation pharmacokinetic approach to evaluate the effect of CYP2D6, CYP3A, ABCB1, POR and NR1I2 genotypes on donepezil clearance.Population pharmacokinetic modeling of the association between 63396C->T pregnane X receptor polymorphism and unboosted atazanavir clearance.Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium FerulateRegulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor.Frequency of genetic polymorphisms of PXR gene in the Brazilian population.The SLCO1B1 rs4149032 polymorphism is highly prevalent in South Africans and is associated with reduced rifampin concentrations: dosing implications.Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugsExploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in MalawiansSpecial populations and pharmacogenetic issues in tuberculosis drug development and clinical researchGender-Dimorphic Impact of PXR Genotype and Haplotype on Hepatotoxicity During Antituberculosis TreatmentInterindividual Variability in Cytochrome P450-Mediated Drug Metabolism.Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" ProblemDiscordant associations between SLCO1B1 521T→C and plasma levels of ritonavir-boosted protease inhibitors in AIDS clinical trials group study A5146.Genetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus.Association of a single-nucleotide polymorphism in the pregnane X receptor (PXR 63396C-->T) with reduced concentrations of unboosted atazanavir.PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 StudyAssociations of CYP3A4, NR1I2, CYP2C19 and P2RY12 polymorphisms with clopidogrel resistance in Chinese patients with ischemic stroke.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variationThe steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio)Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women.Predicting potentially functional SNPs in drug-response genes.The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.The missing linkage: what pharmacogenetic associations are left to find in CYP3A?Associations of ABCB1, NFKB1, CYP3A, and NR1I2 polymorphisms with cyclosporine trough concentrations in Chinese renal transplant recipients.Pharmacogenetics of drug-induced liver injury.Pregnane X receptor polymorphisms associated with human diseases.Pharmacogenomics of acetaminophen in pediatric populations: a moving target.The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine.Pregnane X receptor, constitutive androstane receptor and hepatocyte nuclear factors as emerging players in cancer precision medicine.
P2860
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P2860
Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@en
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@nl
type
label
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@en
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@nl
prefLabel
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@en
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@nl
P2093
P356
P1476
Novel single nucleotide polymo ...... iation with CYP3A4 expression.
@en
P2093
Erin Schuetz
Jatinder Lamba
Raman Venkataramanan
Vishal Lamba
P304
P356
10.1124/DMD.107.016600
P577
2007-10-09T00:00:00Z