Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells.
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Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemiaSTAT5 in hematopoietic stem cell biology and transplantationBCR-ABL affects STAT5A and STAT5B differentiallyHow Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5Ursolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.A screening-based approach to circumvent tumor microenvironment-driven intrinsic resistance to BCR-ABL+ inhibitors in Ph+ acute lymphoblastic leukemiaCombined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemiaIdentification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.Alternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond.Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia.Control of Pim2 kinase stability and expression in transformed human haematopoietic cellsMethyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cellsTargeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia.Comprehensive Proteomic Analysis of Human Erythropoiesis.Cellular reprogramming and hepatocellular carcinoma development.Oxidative metabolism in cancer: A STAT affair?Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy.Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2.Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.Identification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cellsOncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses.STAT3 as a mediator of BCR-ABL1-independent resistance in chronic myeloid leukemia.Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b.[Mechanisms of EGF regulation of COX-2 through the STAT5 signaling pathway in human lung adenocarcinoma A549 cells].[STAT5, a new therapeutic target against the relapse of chronic myelogenous leukemia?].A pharmacodynamic model of Bcr-Abl signalling in chronic myeloid leukaemia.A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells.Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia.The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro.The Cooperative Relationship between STAT5 and Reactive Oxygen Species in Leukemia: Mechanism and Therapeutic PotentialElevated PTPN2 expression is associated with inferior molecular response in de-novo chronic myeloid leukaemia patients
P2860
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P2860
Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells.
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2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Differential contributions of ...... eukemia stem/progenitor cells.
@en
Differential contributions of ...... eukemia stem/progenitor cells.
@nl
type
label
Differential contributions of ...... eukemia stem/progenitor cells.
@en
Differential contributions of ...... eukemia stem/progenitor cells.
@nl
prefLabel
Differential contributions of ...... eukemia stem/progenitor cells.
@en
Differential contributions of ...... eukemia stem/progenitor cells.
@nl
P2093
P50
P1433
P1476
Differential contributions of ...... eukemia stem/progenitor cells.
@en
P2093
Imen Najjar
Jean-Claude Chomel
Luana Casetti
Sylvie Augé
Séverine Martin-Lannerée
P304
P356
10.1158/0008-5472.CAN-12-3955
P407
P577
2013-02-11T00:00:00Z