Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system.
about
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cellsThe CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturationColony-stimulating factor 1 promotes progression of mammary tumors to malignancySilencing and un-silencing of tetracycline-controlled genes in neuronsAn inducible and reversible mouse genetic rescue system.The B cell antigen receptor and overexpression of MYC can cooperate in the genesis of B cell lymphomasGenetically engineered ERα-positive breast cancer mouse models.NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitroTemporally and spatially controlled expression of transgenes in embryonic and adult tissues.Development of a unique system for spatiotemporal and lineage-specific gene expression in mice.The protooncogene MYC can break B cell toleranceIRF4 is a suppressor of c-Myc induced B cell leukemia.Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesisAn essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation.VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms.Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary glandCre-mediated gene deletion in the mammary gland.Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lungEvidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.Targeted expression of GLI1 in the salivary glands results in an altered differentiation program and hyperplasia.Shh is required for Tabby hair follicle development.KLF4 suppresses transformation of pre-B cells by ABL oncogenesImpaired neural development caused by inducible expression of Axin in transgenic mice.Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice.ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancerSOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.Noncanonical roles of the immune system in eliciting oncogene addictionOncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine.Longitudinal analysis of mammogenesis using a novel tetracycline-inducible mouse model and in vivo imaging.Analysis of the temporal requirement for eda in hair and sweat gland development.Diverse strategies for tetracycline-regulated inducible gene expression.Salivary gland organogenesis.PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.MYC regulates the antitumor immune response through CD47 and PD-L1Prolactin signaling in mammary gland development.Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice.AKT3 drives adenoid cystic carcinoma development in salivary glands.
P2860
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P2860
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Conditional gene expression in ...... etracycline responsive system.
@en
Conditional gene expression in ...... etracycline responsive system.
@nl
type
label
Conditional gene expression in ...... etracycline responsive system.
@en
Conditional gene expression in ...... etracycline responsive system.
@nl
prefLabel
Conditional gene expression in ...... etracycline responsive system.
@en
Conditional gene expression in ...... etracycline responsive system.
@nl
P2093
P356
P1476
Conditional gene expression in ...... etracycline responsive system.
@en
P2093
P304
P356
10.1002/JCB.240590407
P577
1995-12-01T00:00:00Z