about
P185
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsInhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell deathFlux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkBBasal Forebrain Atrophy Contributes to Allocentric Navigation Impairment in Alzheimer's Disease PatientsTertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner.Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease.Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation.Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosisThe effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretaseAn intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor functionThe p75 neurotrophin receptor.Spatial navigation in young versus older adults.Post-synaptic scaffolding protein interactions with glutamate receptors in synaptic dysfunction and Alzheimer's disease.Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR).Local versus long-range neurotrophin receptor signalling: endosomes are not just carriers for axonal transport.Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons.A microarray study of post-mortem mRNA degradation in mouse brain tissue.Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase.Zinc-mediated neuronal death is dependent on Trk activation.Apoptosis and schizophrenia: a pilot study based on dermal fibroblast cell lines.G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity.The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours.p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis.The role of p75NTR in cholinergic basal forebrain structure and function.Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model.Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor.Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts.An exercise path to preventing Alzheimer's disease: An Editorial Highlight on 'Exercise and BDNF reduce Ab production by enhancing α-secretase processing of APP'.Reduction in post-synaptic scaffolding PSD-95 and SAP-102 protein levels in the Alzheimer inferior temporal cortex is correlated with disease pathology.p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells.Copper induced oxidation of serotonin: analysis of products and toxicity.Cholinergic Basal Forebrain Lesion Decreases Neurotrophin Signaling without Affecting Tau Hyperphosphorylation in Genetically Susceptible Mice.Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease.Up-regulation of sortilin mediated by amyloid-β and p75(NTR): safety lies in the middle course.Acute Down-regulation of BDNF Signaling Does Not Replicate Exacerbated Amyloid-β Levels and Cognitive Impairment Induced by Cholinergic Basal Forebrain Lesion.Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment.p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate.
P50
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P50
description
medical researcher
@en
wetenschapper
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name
Elizabeth J. Coulson
@ast
Elizabeth J. Coulson
@en
Elizabeth J. Coulson
@es
Elizabeth J. Coulson
@nl
Elizabeth J. Coulson
@sl
Elizabeth J. Coulson
@sq
type
label
Elizabeth J. Coulson
@ast
Elizabeth J. Coulson
@en
Elizabeth J. Coulson
@es
Elizabeth J. Coulson
@nl
Elizabeth J. Coulson
@sl
Elizabeth J. Coulson
@sq
prefLabel
Elizabeth J. Coulson
@ast
Elizabeth J. Coulson
@en
Elizabeth J. Coulson
@es
Elizabeth J. Coulson
@nl
Elizabeth J. Coulson
@sl
Elizabeth J. Coulson
@sq
P1053
C-8766-2009
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6602573594
P184
P21
P31
P3829
P496
0000-0003-3783-6197