Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines.
about
Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cellsMaritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expressionPotent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).Small-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites.Small molecule Mcl-1 inhibitors for the treatment of cancer.Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products.Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner.The selectivity of Marinopyrrole A to induce apoptosis in MCL1high BCL2low expressing myeloma cells is related to its ability to impair protein translation.
P2860
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P2860
Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@en
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@nl
type
label
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@en
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@nl
prefLabel
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@en
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@nl
P2093
P2860
P356
P1476
Purported Mcl-1 inhibitor mari ...... or Mcl-1-dependent cell lines.
@en
P2093
C C Hughes
J M Eichhorn
S E Alford
T C Chambers
P2860
P356
10.1038/CDDIS.2013.411
P577
2013-10-24T00:00:00Z