N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
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Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthaseStructural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoformsDevelopment of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase.Current trends in QSAR on NO donors and inhibitors of nitric oxide synthase (NOS)*.Synthesis, structure, and biological activity of novel heterocyclic sulfonyl-carboximidamides.Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersDesign of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases.Recent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors.Arginine-based inhibitors of nitric oxide synthase: therapeutic potential and challenges.Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase.1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
P2860
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P2860
N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
N-Phenylamidines as selective ...... nstration of in vivo activity.
@en
N-Phenylamidines as selective ...... nstration of in vivo activity.
@nl
type
label
N-Phenylamidines as selective ...... nstration of in vivo activity.
@en
N-Phenylamidines as selective ...... nstration of in vivo activity.
@nl
prefLabel
N-Phenylamidines as selective ...... nstration of in vivo activity.
@en
N-Phenylamidines as selective ...... nstration of in vivo activity.
@nl
P2093
P356
P1476
N-Phenylamidines as selective ...... nstration of in vivo activity.
@en
P2093
Burnette TC
Collins JL
Furfine ES
Oplinger JA
Shearer BG
P304
P356
10.1021/JM980072P
P407
P577
1998-07-01T00:00:00Z