Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
about
Ribosomopathies: how a common root can cause a tree of pathologiesProgress towards mechanism-based treatment for Diamond-Blackfan anemiaA CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish.Transcriptome analysis of the zebrafish model of Diamond-Blackfan anemia from RPS19 deficiency via p53-dependent and -independent pathways.Genomic characterization of the inherited bone marrow failure syndromes.Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19.Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families.Nucleolar stress with and without p53.The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.Cellular differences in protein synthesis regulate tissue homeostasis.Ribosomal proteins: functions beyond the ribosomeAssessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing.p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT PathwayMutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish.Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.Hooked! Modeling human disease in zebrafish.A liaison between mTOR signaling, ribosome biogenesis and cancerRibosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients.Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells.Scission of the p53-MDM2 Loop by Ribosomal Proteins.Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish.Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitorsControl of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome.FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.How Ribosomes Translate Cancer.Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis.Rare Genetic Blood Disease Modeling in Zebrafish
P2860
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P2860
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@en
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@nl
type
label
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@en
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@nl
prefLabel
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@en
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@nl
P2093
P2860
P1476
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
@en
P2093
Alison M Taylor
Caroline E Burns
Jessica M Humphries
Leonard I Zon
Richard M White
Ryan D Murphey
P2860
P304
228-237.e5
P356
10.1016/J.EXPHEM.2011.11.007
P577
2011-11-25T00:00:00Z