about
T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen TargetingA molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cellsDeterminants of gliadin-specific T cell selection in celiac diseaseModification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognitionComparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells.MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usageProgression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccinationProgrammed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia.Monoclonal TCR-redirected tumor cell killing.Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques.A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years.Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramersViolation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytesClonality of HTLV-2 in natural infection.A recombinant modified vaccinia ankara vaccine encoding Epstein-Barr Virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer.Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cellsRole of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation.CD8+ TCR Bias and Immunodominance in HIV-1 Infection.Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamicsβ-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure.Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV DiseaseHoloendemic malaria exposure is associated with altered Epstein-Barr virus-specific CD8(+) T-cell differentiation.HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers.High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow.Cellular-level versus receptor-level response threshold hierarchies in T-cell activation.Purity of transferred CD8(+) T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1.Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux.CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells.Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8+ T Cells.Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance.Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide-MHC Class II Multimers.CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy.Immune activation suppresses initiation of lytic Epstein-Barr virus infection.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Kristin Ladell
@ast
Kristin Ladell
@en
Kristin Ladell
@es
Kristin Ladell
@nl
Kristin Ladell
@sl
type
label
Kristin Ladell
@ast
Kristin Ladell
@en
Kristin Ladell
@es
Kristin Ladell
@nl
Kristin Ladell
@sl
prefLabel
Kristin Ladell
@ast
Kristin Ladell
@en
Kristin Ladell
@es
Kristin Ladell
@nl
Kristin Ladell
@sl
P1053
C-8301-2013
P106
P21
P2798
P31
P3829
P496
0000-0002-9856-2938