T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting - Wikidata - awgldk - TriplyDB

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

http://www.wikidata.org/entity/Q27672418

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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens.CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope.Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor.Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics Antigenic variability: Obstacles on the road to vaccines against traditionally difficult targets.Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.Using Global Analysis to Extend the Accuracy and Precision of Binding Measurements with T cell Receptors and Their Peptide/MHC Ligands.Mobilizing and evaluating anticancer T cells: pitfalls and solutions.Engineering α-fetoprotein-based gene vaccines to prevent and treat hepatocellular carcinoma: review and future prospects.Individual MHCI-Restricted T-Cell Receptors are Characterized by a Unique Peptide Recognition Signature.Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes.Advances in T-cell epitope engineering.Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma.Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

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T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

http://www.wikidata.org/entity/Q27672418

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

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2012年论文

@wuu

name

T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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type

label

T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

@ast

T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

@en

T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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JBC.M112.386409

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Journal of Biological Chemistry

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T-cell Receptor-optimized Pept ...... Can Enhance Antigen Targeting

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Anna Fuller

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Anna Lissina

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Brian M Baker

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Emily S J Edwards

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Emma Gostick

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Florian Madura

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Garry M Dolton

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Johanne Pentier

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Julia Ekeruche-Makinde

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Katherine K Matthews

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P2860

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans

Thymic selection generates a large T cell pool recognizing a self-peptide in humans

A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site

Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor

Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A0201: Implications for WT1-based cancer therapeutics

Coot: model-building tools for molecular graphics

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37269-81

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1618349

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10.1074/JBC.M112.386409

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44

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287

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Andrew K Sewell

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2012-10-26T00:00:00Z

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