HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

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HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@en

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@nl

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label

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@en

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@nl

prefLabel

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@en

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@nl

P1476

HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.

@en

P2093

Guangwen Cao

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Hai-Xiong Han

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Hong-Juan Liu

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Li Liang

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Li-Jing Wang

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Na Tang

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Tengfei Liu

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Tingting Li

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Wei-Jie Zhou

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Yan-Qing Ding

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P2860

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor

Identification of stem cells in small intestine and colon by marker gene Lgr5

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Long-term culture of genome-stable bipotent stem cells from adult human liver

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.

Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice.

P2888

s41467-017-01341-6

P304

1175

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P31

scholarly article

P356

10.1038/S41467-017-01341-6

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P407

English

P433

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P478

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P577

2017-10-27T00:00:00Z

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P698

29079780

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P932

5660090

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