Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants. - Wikidata - awgldk - TriplyDB

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants.

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants.

http://www.wikidata.org/entity/Q42643970

about

Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Maternal exposure to household chemicals and risk of infant leukemia: a report from the Children's Oncology Group A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.Excess congenital non-synonymous variation in leukemia-associated genes in MLL- infant leukemia: a Children's Oncology Group report.Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia.MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: a Children's Oncology Group (COG) study.Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study.A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification.The pathogenesis of mixed-lineage leukemia.Genetic variants modify susceptibility to leukemia in infants: a Children's Oncology Group report.CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Treatment of infant leukemias: challenge and promise.RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.Maternal prenatal cigarette, alcohol and illicit drug use and risk of infant leukaemia: a report from the Children's Oncology Group Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis.MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.The evolution of clinical trials for infant acute lymphoblastic leukemia.Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia.MicroRNAs in acute leukemia: from biological players to clinical contributors.MLL-SEPTIN gene fusions in hematological malignancies.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis.HMGA2 as a potential molecular target in KMT2A-AFF1-positive infant acute lymphoblastic leukaemia.Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL.Mouse models of MLL leukemia: recapitulating the human disease Prognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia.The IRX1/HOXA connection: insights into a novel t(4;11)- specific cancer mechanism MLL-AF4 driven leukemogenesis: what are we missing?MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations.Multiple clonal MLL fusions in a patient receiving CHOP-based chemotherapy.

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P2860

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants.

http://www.wikidata.org/entity/Q42643970

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Gene expression profiling-base ...... hoblastic leukemia in infants.

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Gene expression profiling-base ...... hoblastic leukemia in infants.

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type

label

Gene expression profiling-base ...... hoblastic leukemia in infants.

@en

Gene expression profiling-base ...... hoblastic leukemia in infants.

@nl

prefLabel

Gene expression profiling-base ...... hoblastic leukemia in infants.

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Gene expression profiling-base ...... hoblastic leukemia in infants.

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Dominique J P M Stumpel

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Jill A P Hagelstein

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Maria G Valsecchi

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Marieke H van der Linden

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Paola de Lorenzo

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Pauline Schneider

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