Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
about
Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiensEpstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferaseMolecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrRThe structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferaseStructural analyses reveal two distinct families of nucleoside phosphorylasesBiochemical characterization of uracil phosphoribosyltransferase from Mycobacterium tuberculosisTargeting purine and pyrimidine metabolism in human apicomplexan parasitesWhole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondiiClade-specific flucytosine resistance is due to a single nucleotide change in the FUR1 gene of Candida albicans.UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan.Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution.Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs.Screening for small molecule inhibitors of Toxoplasma gondii.Molecular mechanisms of primary resistance to flucytosine in Candida albicans.Sparse networks of directly coupled, polymorphic, and functional side chains in allosteric proteins.Uracil salvage pathway in Lactobacillus plantarum: Transcription and genetic studies.Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii.
P2860
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P2860
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Crystal structures of Toxoplas ...... imination and prodrug binding.
@en
Crystal structures of Toxoplas ...... imination and prodrug binding.
@nl
type
label
Crystal structures of Toxoplas ...... imination and prodrug binding.
@en
Crystal structures of Toxoplas ...... imination and prodrug binding.
@nl
prefLabel
Crystal structures of Toxoplas ...... imination and prodrug binding.
@en
Crystal structures of Toxoplas ...... imination and prodrug binding.
@nl
P2093
P2860
P356
P1433
P1476
Crystal structures of Toxoplas ...... rimination and prodrug binding
@en
P2093
M A Schumacher
R G Brennan
P2860
P304
P356
10.1093/EMBOJ/17.12.3219
P407
P577
1998-06-01T00:00:00Z