New therapeutic targets in ulcerative colitis: the importance of ion transporters in the human colon.
about
Mechanisms Underlying Dysregulation of Electrolyte Absorption in Inflammatory Bowel Disease-Associated DiarrheaReduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine ColitisLineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cellsLoss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation.Downregulation of the NHE3-binding PDZ-adaptor protein PDZK1 expression during cytokine-induced inflammation in interleukin-10-deficient mice.Transport via the transcytotic pathway makes prostasin available as a substrate for matriptaseProbiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells.Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.NHE3 modulates the severity of colitis in IL-10-deficient miceMaternal antibiotic-induced early changes in microbial colonization selectively modulate colonic permeability and inducible heat shock proteins, and digesta concentrations of alkaline phosphatase and TLR-stimulants in swine offspring.Evidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitisENaCs and ASICs as therapeutic targets.Transcriptional regulation of the intestinal luminal Na⁺ and Cl⁻ transporters.The SLC26 gene family of anion transporters and channels.Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C.High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine.Reduced colonic microbial diversity is associated with colitis in NHE3-deficient micePathophysiology of Intestinal Na+/H+ exchange.Intestinal inflammation and the enterocyte transportome.Epithelial transport in inflammatory bowel diseases.Role of epithelial ion transports in inflammatory bowel disease.Effect of NSAIDs on Na⁺/H⁺ exchanger activity in rat colonic crypts.Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on "Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells"Insights into a possible influence on gut microbiota and intestinal barrier function during chronic exposure of mice to imazalil.Epigenetic Modulation of Intestinal Na(+)/H(+) Exchanger-3 Expression.Tumor necrosis factor-α acts reciprocally with solute carrier family 26, member 3, (downregulated-in-adenoma) and reduces its expression, leading to intestinal inflammation.SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis.Bile acids inhibit Na⁺/H⁺ exchanger and Cl⁻/HCO₃⁻ exchanger activities via cellular energy breakdown and Ca²⁺ overload in human colonic crypts
P2860
Q28081517-7F4045E4-4CD0-4AAA-AA4A-BFBCDA8DB316Q28601112-892EDE2F-640B-46E7-8C81-B0ED6F763822Q31143812-FCA56034-C5A5-4EF7-807E-E81BBAC43975Q33664886-673920F3-0E6F-46A1-BFAB-D30E733C9CC5Q34357992-21CC1F00-F43E-4CFE-9CB7-A93BA58CAE39Q34568634-0D0B8D24-B745-476C-83B2-2A6852187353Q34726615-08C03C33-741E-48D6-8EA0-7473A233950FQ34989488-B6CD393B-0C54-4DB4-85B6-7C566CF058C6Q35057022-AE559AB3-8278-4362-8BB8-D2B25C8DCEC9Q35090872-57CDDE7F-3B18-43D4-88BE-894F88F22BC4Q35252041-8E44C8A2-06B5-42EE-B750-3FF590EA8EB6Q35900722-F8D3608A-5443-459C-9D38-4FB8FB43949DQ36039419-DB6EDDCF-D54C-4B7A-BAAE-F38CB0FEF8CEQ36700234-9933AA66-8868-47EC-BC13-8DE04435F5E5Q37156328-9DD530EB-6D16-42BC-B47D-2EC12CC5462EQ37323213-BBB893DB-7DF7-43AC-9B7D-C3B1DEE2ABB0Q37342051-E2F5B03B-972E-4A45-9E14-05F373ACCA92Q37585753-CB2B816A-CB88-4F9A-9E52-09651DD5DC60Q37905164-B19C4EE0-DF54-4605-A33F-5A3C664B2C9EQ38201235-ABE1DC6C-BA95-4B6F-8812-96BF0C0D2D48Q38690199-F1AACBEC-D05B-4B5C-8130-0C90B3BB83F1Q39226084-42F7CE2C-E0BB-459A-87D3-5D5E3D0DB48CQ42551772-DC856D5D-AEFA-439E-8182-FD28A7EC1B6EQ46268131-8F5D5019-97D7-4E4F-BA84-4C3F862AC70FQ47372874-144E87FF-86D9-4A64-A488-0FF4FF939AD9Q49500705-7440A672-181A-4EB7-8F05-A86D820E3518Q50058415-6A23FFD4-473C-4D23-9202-9D0E3D9A9C02Q57107234-03AF462D-C8E8-423C-BA15-9B17866EF131
P2860
New therapeutic targets in ulcerative colitis: the importance of ion transporters in the human colon.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
New therapeutic targets in ulc ...... ansporters in the human colon.
@en
New therapeutic targets in ulc ...... ansporters in the human colon.
@nl
type
label
New therapeutic targets in ulc ...... ansporters in the human colon.
@en
New therapeutic targets in ulc ...... ansporters in the human colon.
@nl
prefLabel
New therapeutic targets in ulc ...... ansporters in the human colon.
@en
New therapeutic targets in ulc ...... ansporters in the human colon.
@nl
P2093
P2860
P356
P1476
New therapeutic targets in ulc ...... ransporters in the human colon
@en
P2093
Andrea Schnúr
Brigitte Riederer
Ferenc Nagy
György Lázár
Gábor Varga
Jessica Hubricht
Klaudia Farkas
Lisa Ludolph
Marianna Király
Péter Hegyi
P2860
P304
P356
10.1002/IBD.21432
P577
2010-08-18T00:00:00Z