A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus.
about
The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerusOrganization and transcriptional analysis of a six-gene cluster around the rplK-rplA operon of Corynebacterium glutamicum encoding the ribosomal proteins L11 and L1.Investigation of the Streptomyces clavuligerus cephamycin C gene cluster and its regulation by the CcaR protein.Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus.Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerusApplications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production.Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus.The enzymes of β-lactam biosynthesis.The LysR-type transcriptional regulator VirR is required for expression of the virulence gene vapA of Rhodococcus equi ATCC 33701The Pathway-Specific Regulator ClaR of Streptomyces clavuligerus Has a Global Effect on the Expression of Genes for Secondary Metabolism and DifferentiationAlanylclavam biosynthetic genes are clustered together with one group of clavulanic acid biosynthetic genes in Streptomyces clavuligerus.Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.Recombinant organisms for production of industrial products.Biosynthesis of clavam metabolites.Clavulanic acid production by Streptomyces clavuligerus: biogenesis, regulation and strain improvement.CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus.Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways.Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus.Proteomics analysis of global regulatory cascades involved in clavulanic acid production and morphological development in Streptomyces clavuligerus.Expression of ccaR, encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus, is dependent on bldG.Molecular Analysis of the Clavulanic Acid Regulatory Gene Isolated from an Iranian Strain of Streptomyces Clavuligerus , PTCC 1709.Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerusInduction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.Carboxyethylarginine synthase genes show complex cross-regulation in Streptomyces clavuligerus.An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus.Asm8, a specific LAL-type activator of 3-amino-5-hydroxybenzoate biosynthesis in ansamitocin production.Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping.Coordination of glycerol utilization and clavulanic acid biosynthesis to improve clavulanic acid production in Streptomyces clavuligerus.Engineering of the LysR family transcriptional regulator FkbR1 and its target gene to improve ascomycin production.Transcriptional organization of ThnI-regulated thienamycin biosynthetic genes in Streptomyces cattleya.
P2860
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P2860
A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@en
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@nl
type
label
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@en
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@nl
prefLabel
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@en
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@nl
P2093
P2860
P1476
A pathway-specific transcripti ...... in Streptomyces clavuligerus.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2958.1998.00731.X
P407
P577
1998-02-01T00:00:00Z