Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus.
about
X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene clusterThe paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerusTwo sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerusSelf-resistance in Streptomyces, with Special Reference to β-Lactam AntibioticsCrystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathwayStructural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathwayCharacterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus.A comparison of the clavam biosynthetic gene clusters in Streptomyces antibioticus Tü1718 and Streptomyces clavuligerus.The enzymes of β-lactam biosynthesis.ORF17 from the clavulanic acid biosynthesis gene cluster catalyzes the ATP-dependent formation of N-glycyl-clavaminic acid.The Pathway-Specific Regulator ClaR of Streptomyces clavuligerus Has a Global Effect on the Expression of Genes for Secondary Metabolism and DifferentiationAlanylclavam biosynthetic genes are clustered together with one group of clavulanic acid biosynthetic genes in Streptomyces clavuligerus.Biosynthesis of clavam metabolites.Clavulanic acid production by Streptomyces clavuligerus: biogenesis, regulation and strain improvement.Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus.Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064.Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways.Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus.Two oligopeptide-permease-encoding genes in the clavulanic acid cluster of Streptomyces clavuligerus are essential for production of the beta-lactamase inhibitor.Molecular Analysis of the Clavulanic Acid Regulatory Gene Isolated from an Iranian Strain of Streptomyces Clavuligerus , PTCC 1709.Dissection of the stepwise mechanism to beta-lactam formation and elucidation of a rate-determining conformational change in beta-lactam synthetaseExpression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping.Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus.
P2860
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P2860
Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@ast
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@en
type
label
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@ast
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@en
prefLabel
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@ast
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@en
P2093
P2860
P1476
Expansion of the clavulanic ac ...... by Streptomyces clavuligerus.
@en
P2093
P2860
P304
P356
10.1128/JB.182.14.4087-4095.2000
P407
P577
2000-07-01T00:00:00Z